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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
41.21
Human Site:
Y355
Identified Species:
60.44
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
Y355
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
Y355
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Dog
Lupus familis
XP_544655
466
52994
Y355
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
Y354
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Rat
Rattus norvegicus
Q5XIK8
465
52764
Y354
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
F316
L
E
D
A
A
L
T
F
P
V
L
F
Q
D
V
Chicken
Gallus gallus
Q5F3Z7
466
52851
Y355
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Frog
Xenopus laevis
Q801R4
466
52941
Y355
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
Y358
F
T
A
S
K
K
V
Y
A
D
K
L
L
N
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
D185
L
N
R
I
F
I
I
D
N
S
P
G
A
Y
R
Honey Bee
Apis mellifera
XP_395439
486
56215
Y375
F
T
A
S
K
R
V
Y
A
N
K
L
M
N
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
Y374
F
T
A
S
K
R
V
Y
A
D
K
L
L
N
L
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
E185
V
D
N
G
I
P
I
E
S
W
F
E
D
R
S
Maize
Zea mays
NP_001170732
254
29521
N196
A
F
G
F
Q
L
D
N
G
I
P
I
E
S
W
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
W247
N
G
V
P
I
E
S
W
F
N
D
P
S
D
K
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
T339
I
G
R
P
L
S
E
T
I
I
L
D
N
S
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
0
100
100
100
N.A.
0
73.3
N.A.
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
6.6
100
N.A.
100
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
0
0
N.A.
0
0
N.A.
P-Site Similarity:
13.3
20
N.A.
26.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
0
63
7
7
0
0
0
63
0
0
0
7
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
7
0
0
0
7
7
0
57
7
7
7
13
0
% D
% Glu:
0
7
0
0
0
7
7
7
0
0
0
7
7
0
0
% E
% Phe:
63
7
0
7
7
0
0
7
7
0
7
7
0
0
0
% F
% Gly:
0
13
7
7
0
0
0
0
7
0
0
7
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
0
7
13
7
13
0
7
13
0
7
0
0
50
% I
% Lys:
0
0
0
0
63
50
0
0
0
0
63
0
0
0
7
% K
% Leu:
13
0
0
0
7
13
0
0
0
0
13
63
57
0
13
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
7
7
7
0
0
0
0
7
7
13
0
0
7
63
0
% N
% Pro:
0
0
0
13
0
7
0
0
7
0
13
7
0
0
7
% P
% Gln:
0
0
0
0
7
0
0
0
0
0
0
0
7
0
0
% Q
% Arg:
0
0
13
0
0
13
0
0
0
0
0
0
0
7
7
% R
% Ser:
0
0
0
63
0
7
7
0
7
7
0
0
7
13
7
% S
% Thr:
0
63
0
0
0
0
7
7
0
0
0
0
0
0
0
% T
% Val:
7
0
7
0
0
0
63
0
0
7
0
0
0
0
7
% V
% Trp:
0
0
0
0
0
0
0
7
0
7
0
0
0
0
7
% W
% Tyr:
0
0
0
0
0
0
0
63
0
0
0
0
0
7
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _