KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
27.88
Human Site:
Y239
Identified Species:
40.89
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
Y239
P
V
T
P
D
S
G
Y
S
S
A
H
A
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
Y239
P
V
T
P
D
S
G
Y
S
S
A
H
A
E
A
Dog
Lupus familis
XP_544655
466
52994
Y239
P
V
T
P
D
S
G
Y
S
S
A
H
A
E
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
Y238
P
V
T
P
E
S
G
Y
S
S
A
H
A
E
A
Rat
Rattus norvegicus
Q5XIK8
465
52764
Y238
P
V
A
P
E
S
G
Y
S
S
A
H
A
E
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
G200
S
T
T
A
S
T
N
G
A
A
Y
S
S
P
A
Chicken
Gallus gallus
Q5F3Z7
466
52851
Y239
P
V
S
P
D
S
G
Y
S
S
A
H
A
E
A
Frog
Xenopus laevis
Q801R4
466
52941
Y239
P
V
S
P
E
S
G
Y
S
S
A
H
A
E
A
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
P242
N
S
N
Y
P
D
V
P
P
S
P
P
A
E
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
E69
T
L
V
L
D
L
D
E
T
L
I
H
S
H
H
Honey Bee
Apis mellifera
XP_395439
486
56215
C259
S
E
E
I
V
E
S
C
D
M
E
N
M
V
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
Y258
C
Q
M
Q
Y
A
T
Y
E
P
I
E
P
D
F
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
P69
L
V
H
S
A
L
E
P
C
N
D
A
D
F
T
Maize
Zea mays
NP_001170732
254
29521
H80
D
L
D
E
T
L
V
H
S
T
L
E
H
C
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
G131
H
S
T
L
E
P
C
G
E
V
D
F
T
F
P
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
E223
L
L
P
P
K
L
Q
E
F
Q
Q
K
K
C
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
93.3
86.6
N.A.
13.3
93.3
86.6
20
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
93.3
N.A.
40
100
100
20
N.A.
33.3
6.6
N.A.
20
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
6.6
6.6
N.A.
6.6
6.6
N.A.
P-Site Similarity:
13.3
26.6
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
7
7
7
0
0
7
7
44
7
50
0
50
% A
% Cys:
7
0
0
0
0
0
7
7
7
0
0
0
0
13
0
% C
% Asp:
7
0
7
0
32
7
7
0
7
0
13
0
7
7
0
% D
% Glu:
0
7
7
7
25
7
7
13
13
0
7
13
0
50
7
% E
% Phe:
0
0
0
0
0
0
0
0
7
0
0
7
0
13
7
% F
% Gly:
0
0
0
0
0
0
44
13
0
0
0
0
0
0
7
% G
% His:
7
0
7
0
0
0
0
7
0
0
0
50
7
7
7
% H
% Ile:
0
0
0
7
0
0
0
0
0
0
13
0
0
0
0
% I
% Lys:
0
0
0
0
7
0
0
0
0
0
0
7
7
0
0
% K
% Leu:
13
19
0
13
0
25
0
0
0
7
7
0
0
0
7
% L
% Met:
0
0
7
0
0
0
0
0
0
7
0
0
7
0
0
% M
% Asn:
7
0
7
0
0
0
7
0
0
7
0
7
0
0
0
% N
% Pro:
44
0
7
50
7
7
0
13
7
7
7
7
7
7
7
% P
% Gln:
0
7
0
7
0
0
7
0
0
7
7
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
13
13
13
7
7
44
7
0
50
50
0
7
13
0
0
% S
% Thr:
7
7
38
0
7
7
7
0
7
7
0
0
7
0
13
% T
% Val:
0
50
7
0
7
0
13
0
0
7
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
7
7
0
0
50
0
0
7
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _