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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
40.91
Human Site:
T400
Identified Species:
60
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
T400
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
T400
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Dog
Lupus familis
XP_544655
466
52994
T400
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
T399
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Rat
Rattus norvegicus
Q5XIK8
465
52764
T399
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
I345
F
L
E
R
M
S
Q
I
Y
E
I
I
L
F
T
Chicken
Gallus gallus
Q5F3Z7
466
52851
T400
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Frog
Xenopus laevis
Q801R4
466
52941
T400
L
G
R
D
L
S
K
T
I
I
I
D
N
S
P
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
T403
L
G
R
D
L
S
K
T
V
I
I
D
N
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
L214
D
P
M
D
T
A
L
L
S
L
L
P
M
L
D
Honey Bee
Apis mellifera
XP_395439
486
56215
T420
L
G
R
D
L
S
K
T
V
I
I
D
N
S
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
T419
L
G
R
D
L
T
K
T
V
I
I
D
N
S
P
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
P214
V
G
V
E
D
V
R
P
L
I
A
K
K
Y
N
Maize
Zea mays
NP_001170732
254
29521
V225
F
L
E
S
L
V
G
V
E
D
V
R
P
Y
I
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
I276
V
E
D
V
R
P
M
I
A
K
K
F
N
L
R
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
D368
S
W
F
S
D
T
H
D
N
E
L
L
D
I
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
100
100
93.3
N.A.
6.6
93.3
N.A.
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
26.6
100
N.A.
100
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
13.3
6.6
N.A.
6.6
0
N.A.
P-Site Similarity:
40
13.3
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
7
0
0
7
0
7
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
7
0
7
69
13
0
0
7
0
7
0
63
7
0
7
% D
% Glu:
0
7
13
7
0
0
0
0
7
13
0
0
0
0
0
% E
% Phe:
13
0
7
0
0
0
0
0
0
0
0
7
0
7
0
% F
% Gly:
0
69
0
0
0
0
7
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
13
44
69
69
7
0
7
13
% I
% Lys:
0
0
0
0
0
0
63
0
0
7
7
7
7
0
0
% K
% Leu:
63
13
0
0
69
0
7
7
7
7
13
7
7
13
0
% L
% Met:
0
0
7
0
7
0
7
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
7
0
0
0
69
0
7
% N
% Pro:
0
7
0
0
0
7
0
7
0
0
0
7
7
0
63
% P
% Gln:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
63
7
7
0
7
0
0
0
0
7
0
0
7
% R
% Ser:
7
0
0
13
0
63
0
0
7
0
0
0
0
63
0
% S
% Thr:
0
0
0
0
7
13
0
63
0
0
0
0
0
0
7
% T
% Val:
13
0
7
7
0
13
0
7
19
0
7
0
0
0
0
% V
% Trp:
0
7
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
7
0
0
0
0
13
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _