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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
19.7
Human Site:
S69
Identified Species:
28.89
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
S69
K
E
E
R
E
N
P
S
K
R
S
R
I
E
R
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
S69
K
E
E
R
E
N
P
S
K
R
S
R
I
E
R
Dog
Lupus familis
XP_544655
466
52994
S69
K
E
E
R
E
N
P
S
K
R
S
R
I
E
R
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
S69
K
E
E
R
E
N
P
S
K
R
S
R
I
E
R
Rat
Rattus norvegicus
Q5XIK8
465
52764
S69
K
E
E
R
E
N
P
S
K
R
S
R
I
E
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
P38
S
E
V
E
E
R
L
P
V
D
G
E
K
T
Q
Chicken
Gallus gallus
Q5F3Z7
466
52851
A69
K
E
E
R
E
N
P
A
K
R
S
R
I
E
R
Frog
Xenopus laevis
Q801R4
466
52941
A72
K
E
D
R
E
N
P
A
K
R
S
K
V
E
R
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
A69
K
V
E
Q
C
T
P
A
K
R
S
R
V
D
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
Honey Bee
Apis mellifera
XP_395439
486
56215
L69
R
R
R
C
T
H
F
L
K
E
A
C
K
E
N
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
K80
V
D
D
D
V
S
R
K
R
R
R
A
A
E
E
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
Maize
Zea mays
NP_001170732
254
29521
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
T61
G
D
K
M
Q
Y
S
T
P
E
I
L
L
S
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
13.3
93.3
73.3
46.6
N.A.
0
13.3
N.A.
13.3
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
100
100
73.3
N.A.
0
33.3
N.A.
40
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
0
0
N.A.
0
0
N.A.
P-Site Similarity:
0
0
N.A.
0
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
19
0
0
7
7
7
0
0
% A
% Cys:
0
0
0
7
7
0
0
0
0
0
0
7
0
0
7
% C
% Asp:
0
13
13
7
0
0
0
0
0
7
0
0
0
7
0
% D
% Glu:
0
50
44
7
50
0
0
0
0
13
0
7
0
57
7
% E
% Phe:
0
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
7
0
0
0
0
% G
% His:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
7
0
38
0
0
% I
% Lys:
50
0
7
0
0
0
0
7
57
0
0
7
13
0
0
% K
% Leu:
0
0
0
0
0
0
7
7
0
0
0
7
7
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
44
0
0
0
0
0
0
0
0
7
% N
% Pro:
0
0
0
0
0
0
50
7
7
0
0
0
0
0
0
% P
% Gln:
0
0
0
7
7
0
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
7
7
44
0
7
7
0
7
57
7
44
0
0
44
% R
% Ser:
7
0
0
0
0
7
7
32
0
0
50
0
0
7
7
% S
% Thr:
0
0
0
0
7
7
0
7
0
0
0
0
0
7
0
% T
% Val:
7
7
7
0
7
0
0
0
7
0
0
0
13
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _