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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CTDSPL2
All Species:
41.52
Human Site:
S406
Identified Species:
60.89
UniProt:
Q05D32
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05D32
NP_057480.2
466
52999
S406
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001110308
466
52980
S406
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Dog
Lupus familis
XP_544655
466
52994
S406
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q8BG15
465
52794
S405
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Rat
Rattus norvegicus
Q5XIK8
465
52764
S405
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511004
374
42210
F351
Q
I
Y
E
I
I
L
F
T
A
S
K
K
V
Y
Chicken
Gallus gallus
Q5F3Z7
466
52851
S406
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Frog
Xenopus laevis
Q801R4
466
52941
S406
K
T
I
I
I
D
N
S
P
Q
A
F
A
Y
Q
Zebra Danio
Brachydanio rerio
Q08BB5
469
52971
S409
K
T
V
I
I
D
N
S
P
Q
A
F
A
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VRG7
243
28468
L220
L
L
S
L
L
P
M
L
D
A
L
R
F
T
N
Honey Bee
Apis mellifera
XP_395439
486
56215
S426
K
T
V
I
I
D
N
S
P
Q
A
F
G
Y
Q
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_788296
466
52589
S425
K
T
V
I
I
D
N
S
P
Q
A
F
G
Y
Q
Poplar Tree
Populus trichocarpa
XP_002303804
244
28215
Y220
R
P
L
I
A
K
K
Y
N
L
R
Q
K
I
A
Maize
Zea mays
NP_001170732
254
29521
Y231
G
V
E
D
V
R
P
Y
I
A
R
K
F
N
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196747
305
34829
L282
M
I
A
K
K
F
N
L
R
E
K
I
D
A
A
Baker's Yeast
Sacchar. cerevisiae
Q07949
397
44753
I374
H
D
N
E
L
L
D
I
I
P
L
L
E
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.7
99.3
N.A.
97.2
97
N.A.
71.4
93.7
82.6
73.5
N.A.
22.1
42.1
N.A.
46.7
Protein Similarity:
100
N.A.
100
99.5
N.A.
98.5
98.2
N.A.
75.5
97
90.1
82.7
N.A.
34.3
56.3
N.A.
61.5
P-Site Identity:
100
N.A.
100
100
N.A.
100
100
N.A.
6.6
100
100
93.3
N.A.
0
86.6
N.A.
86.6
P-Site Similarity:
100
N.A.
100
100
N.A.
100
100
N.A.
20
100
100
100
N.A.
13.3
93.3
N.A.
93.3
Percent
Protein Identity:
29.1
30.4
N.A.
32.1
25.9
N.A.
Protein Similarity:
39.4
41.6
N.A.
45.9
45.4
N.A.
P-Site Identity:
6.6
0
N.A.
6.6
0
N.A.
P-Site Similarity:
20
6.6
N.A.
13.3
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
0
7
0
0
0
0
19
63
0
50
7
13
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
7
0
7
0
63
7
0
7
0
0
0
7
7
0
% D
% Glu:
0
0
7
13
0
0
0
0
0
7
0
0
7
0
0
% E
% Phe:
0
0
0
0
0
7
0
7
0
0
0
63
13
0
0
% F
% Gly:
7
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% G
% His:
7
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
13
44
69
69
7
0
7
13
0
0
7
0
7
0
% I
% Lys:
63
0
0
7
7
7
7
0
0
0
7
13
13
0
0
% K
% Leu:
7
7
7
7
13
7
7
13
0
7
13
7
0
0
13
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
7
0
0
0
69
0
7
0
0
0
0
7
7
% N
% Pro:
0
7
0
0
0
7
7
0
63
7
0
0
0
0
0
% P
% Gln:
7
0
0
0
0
0
0
0
0
63
0
7
0
0
63
% Q
% Arg:
7
0
0
0
0
7
0
0
7
0
13
7
0
0
0
% R
% Ser:
0
0
7
0
0
0
0
63
0
0
7
0
0
0
0
% S
% Thr:
0
63
0
0
0
0
0
0
7
0
0
0
0
7
0
% T
% Val:
0
7
19
0
7
0
0
0
0
0
0
0
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
0
0
13
0
0
0
0
0
63
7
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _