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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FPGS
All Species:
14.85
Human Site:
S274
Identified Species:
27.22
UniProt:
Q05932
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05932
NP_001018088.1
587
64609
S274
R
D
R
A
Q
Q
I
S
C
P
L
Y
L
C
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001094027
589
64667
S274
R
D
R
A
Q
Q
I
S
C
P
L
Y
L
C
P
Dog
Lupus familis
XP_851481
588
64991
S275
Q
D
R
A
Q
K
I
S
C
P
L
Y
L
C
P
Cat
Felis silvestris
Mouse
Mus musculus
P48760
587
64889
G274
R
D
R
A
Q
Q
I
G
C
P
L
Y
L
C
P
Rat
Rattus norvegicus
NP_001139597
587
65251
S274
R
D
R
A
Q
Q
I
S
C
P
L
Y
L
C
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_998602
572
63143
G276
Q
E
R
A
E
E
V
G
C
S
L
S
V
C
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_397249
440
49749
F161
T
V
L
M
F
N
V
F
L
D
E
H
V
D
V
Nematode Worm
Caenorhab. elegans
Q09509
510
56414
W230
N
K
L
S
E
I
A
W
H
K
A
G
I
F
K
Sea Urchin
Strong. purpuratus
XP_796835
647
71198
E277
K
E
R
A
R
E
K
E
A
S
L
Q
V
V
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
NP_001152065
557
61781
L275
P
E
E
A
M
S
V
L
M
K
R
A
T
E
L
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
NP_196217
571
63327
S286
R
V
L
E
E
K
A
S
E
T
E
V
N
L
E
Baker's Yeast
Sacchar. cerevisiae
Q08645
548
62133
L258
I
V
C
G
V
T
L
L
G
I
D
H
T
F
M
Red Bread Mold
Neurospora crassa
O13492
528
58506
W249
D
T
V
D
K
I
A
W
H
K
A
G
I
M
K
Conservation
Percent
Protein Identity:
100
N.A.
93.8
87
N.A.
81.4
80.9
N.A.
N.A.
N.A.
N.A.
59.9
N.A.
N.A.
32.8
35.9
41.1
Protein Similarity:
100
N.A.
95.9
91.6
N.A.
87.9
87.7
N.A.
N.A.
N.A.
N.A.
72.4
N.A.
N.A.
50.9
50.9
55.3
P-Site Identity:
100
N.A.
100
86.6
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
40
N.A.
N.A.
0
0
26.6
P-Site Similarity:
100
N.A.
100
100
N.A.
93.3
100
N.A.
N.A.
N.A.
N.A.
80
N.A.
N.A.
20
20
60
Percent
Protein Identity:
N.A.
35.6
N.A.
35.6
37.1
34.7
Protein Similarity:
N.A.
49.2
N.A.
50.9
52.1
50.4
P-Site Identity:
N.A.
6.6
N.A.
13.3
0
0
P-Site Similarity:
N.A.
20
N.A.
26.6
13.3
13.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
62
0
0
24
0
8
0
16
8
0
0
0
% A
% Cys:
0
0
8
0
0
0
0
0
47
0
0
0
0
47
0
% C
% Asp:
8
39
0
8
0
0
0
0
0
8
8
0
0
8
0
% D
% Glu:
0
24
8
8
24
16
0
8
8
0
16
0
0
8
8
% E
% Phe:
0
0
0
0
8
0
0
8
0
0
0
0
0
16
0
% F
% Gly:
0
0
0
8
0
0
0
16
8
0
0
16
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
16
0
0
16
0
0
0
% H
% Ile:
8
0
0
0
0
16
39
0
0
8
0
0
16
0
0
% I
% Lys:
8
8
0
0
8
16
8
0
0
24
0
0
0
0
16
% K
% Leu:
0
0
24
0
0
0
8
16
8
0
54
0
39
8
8
% L
% Met:
0
0
0
8
8
0
0
0
8
0
0
0
0
8
8
% M
% Asn:
8
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
0
0
0
0
0
0
0
39
0
0
0
0
54
% P
% Gln:
16
0
0
0
39
31
0
0
0
0
0
8
0
0
0
% Q
% Arg:
39
0
54
0
8
0
0
0
0
0
8
0
0
0
0
% R
% Ser:
0
0
0
8
0
8
0
39
0
16
0
8
0
0
0
% S
% Thr:
8
8
0
0
0
8
0
0
0
8
0
0
16
0
0
% T
% Val:
0
24
8
0
8
0
24
0
0
0
0
8
24
8
8
% V
% Trp:
0
0
0
0
0
0
0
16
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
39
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _