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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EN1
All Species:
4.85
Human Site:
S228
Identified Species:
9.7
UniProt:
Q05925
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05925
NP_001417.3
392
40115
S228
S
D
T
G
G
G
G
S
G
G
G
A
G
S
P
Chimpanzee
Pan troglodytes
XP_001172516
331
34435
S167
S
D
S
G
G
G
G
S
G
G
G
A
G
S
P
Rhesus Macaque
Macaca mulatta
XP_001106130
334
34311
K170
S
L
H
G
G
A
K
K
G
S
D
P
G
G
P
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P09065
401
40932
G237
K
P
S
D
S
G
G
G
S
G
G
N
A
G
S
Rat
Rattus norvegicus
XP_001056699
401
40729
G237
K
P
S
D
S
G
G
G
S
G
G
S
A
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512614
188
20519
A31
P
G
G
P
L
E
G
A
L
K
S
R
G
L
T
Chicken
Gallus gallus
Q05916
333
34497
A170
A
A
G
A
A
G
A
A
K
A
Q
G
D
G
G
Frog
Xenopus laevis
P31538
171
19132
S14
G
P
G
N
P
A
P
S
P
D
S
D
T
P
S
Zebra Danio
Brachydanio rerio
P31533
261
29466
I104
N
A
S
K
K
T
D
I
S
T
D
E
S
L
K
Tiger Blowfish
Takifugu rubipres
Q1KKX0
280
30954
G123
S
D
R
S
T
T
S
G
G
N
A
L
N
K
S
Fruit Fly
Dros. melanogaster
P02836
552
59392
N378
G
A
S
G
S
G
V
N
A
S
S
P
Q
P
Q
Honey Bee
Apis mellifera
P09076
109
12608
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.6
46.1
N.A.
N.A.
91.7
91.2
N.A.
34.4
66
36.9
40
22.1
28.2
20.4
N.A.
N.A.
Protein Similarity:
100
83.4
53.8
N.A.
N.A.
92
91.7
N.A.
38.7
70.4
40.8
48.7
35.2
41.6
23.2
N.A.
N.A.
P-Site Identity:
100
93.3
40
N.A.
N.A.
26.6
26.6
N.A.
13.3
6.6
6.6
0
20
13.3
0
N.A.
N.A.
P-Site Similarity:
100
100
40
N.A.
N.A.
33.3
40
N.A.
20
20
6.6
13.3
20
26.6
0
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
25
0
9
9
17
9
17
9
9
9
17
17
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
17
0
0
9
0
0
9
17
9
9
0
0
% D
% Glu:
0
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
17
9
25
34
25
50
42
25
34
34
34
9
34
34
9
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% I
% Lys:
17
0
0
9
9
0
9
9
9
9
0
0
0
9
9
% K
% Leu:
0
9
0
0
9
0
0
0
9
0
0
9
0
17
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
9
0
0
9
0
0
0
9
0
9
0
9
9
0
0
% N
% Pro:
9
25
0
9
9
0
9
0
9
0
0
17
0
17
25
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
9
% Q
% Arg:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% R
% Ser:
34
0
42
9
25
0
9
25
25
17
25
9
9
17
34
% S
% Thr:
0
0
9
0
9
17
0
0
0
9
0
0
9
0
9
% T
% Val:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _