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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GAD2
All Species:
34.55
Human Site:
S278
Identified Species:
63.33
UniProt:
Q05329
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05329
NP_000809.1
585
65411
S278
P
R
L
I
A
F
T
S
E
H
S
H
F
S
L
Chimpanzee
Pan troglodytes
Q5IS68
594
66879
S287
P
K
L
V
L
F
T
S
E
Q
S
H
Y
S
I
Rhesus Macaque
Macaca mulatta
XP_001101800
540
60175
G266
F
P
E
V
K
E
K
G
M
A
A
V
P
R
L
Dog
Lupus familis
XP_541080
543
61384
V257
L
G
I
G
T
D
N
V
I
E
V
K
C
D
E
Cat
Felis silvestris
Mouse
Mus musculus
P48320
585
65206
S278
P
R
L
I
A
F
T
S
E
H
S
H
F
S
L
Rat
Rattus norvegicus
Q05683
585
65384
S278
P
R
L
I
A
F
T
S
E
H
S
H
F
S
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506641
568
63961
S261
P
R
L
V
A
F
T
S
E
H
S
H
F
S
V
Chicken
Gallus gallus
XP_418596
610
68572
S303
P
R
L
V
A
F
T
S
E
H
S
H
F
S
V
Frog
Xenopus laevis
NP_001079270
563
64077
S256
P
R
L
V
L
F
T
S
E
H
S
H
Y
S
I
Zebra Danio
Brachydanio rerio
NP_001017708
583
65440
S276
P
R
L
V
A
F
T
S
E
H
S
H
F
S
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20228
510
57801
I236
S
D
E
H
G
K
M
I
T
S
E
L
E
R
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_784856
614
68930
S304
P
N
L
V
M
F
T
S
E
Q
S
H
F
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9M0G4
545
60786
L264
I
H
E
E
N
I
R
L
L
K
T
D
S
S
T
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
64.3
90.4
55.2
N.A.
95.7
96
N.A.
88.7
79.3
54.3
78.4
N.A.
47.5
N.A.
N.A.
51.4
Protein Similarity:
100
79.6
91.1
73.3
N.A.
97.2
97.7
N.A.
93.1
84.4
69.4
88.8
N.A.
63.5
N.A.
N.A.
69.5
P-Site Identity:
100
60
6.6
0
N.A.
100
100
N.A.
86.6
86.6
73.3
86.6
N.A.
6.6
N.A.
N.A.
66.6
P-Site Similarity:
100
86.6
20
6.6
N.A.
100
100
N.A.
100
100
93.3
100
N.A.
6.6
N.A.
N.A.
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
39.8
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
47
0
0
0
0
8
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
0
0
8
0
8
0
% D
% Glu:
0
0
24
8
0
8
0
0
70
8
8
0
8
0
8
% E
% Phe:
8
0
0
0
0
70
0
0
0
0
0
0
54
0
0
% F
% Gly:
0
8
0
8
8
0
0
8
0
0
0
0
0
0
0
% G
% His:
0
8
0
8
0
0
0
0
0
54
0
70
0
0
0
% H
% Ile:
8
0
8
24
0
8
0
8
8
0
0
0
0
0
31
% I
% Lys:
0
8
0
0
8
8
8
0
0
8
0
8
0
0
0
% K
% Leu:
8
0
70
0
16
0
0
8
8
0
0
8
0
0
39
% L
% Met:
0
0
0
0
8
0
8
0
8
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
0
% N
% Pro:
70
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% Q
% Arg:
0
54
0
0
0
0
8
0
0
0
0
0
0
16
0
% R
% Ser:
8
0
0
0
0
0
0
70
0
8
70
0
8
77
0
% S
% Thr:
0
0
0
0
8
0
70
0
8
0
8
0
0
0
8
% T
% Val:
0
0
0
54
0
0
0
8
0
0
8
8
0
0
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _