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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3A All Species: 43.64
Human Site: Y776 Identified Species: 73.85
UniProt: Q05086 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05086 NP_000453.2 875 100688 Y776 A L E E T T E Y D G G Y T R D
Chimpanzee Pan troglodytes XP_510256 879 101065 Y780 A L E E T T E Y D G G Y T R D
Rhesus Macaque Macaca mulatta XP_001108510 879 101081 Y780 A L E E T T E Y D G G Y T R D
Dog Lupus familis XP_848240 875 100388 Y776 A L E E T T E Y D G G Y T R D
Cat Felis silvestris
Mouse Mus musculus O08759 885 101157 Y786 A L E E T T E Y D G G Y T R E
Rat Rattus norvegicus Q5PQN1 1057 118521 Y958 E L E K N T E Y K G E Y W A E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514205 825 94298 S727 A H T V T I R S Y V R S A R L
Chicken Gallus gallus XP_416882 880 100974 Y781 A L E E T T E Y D G G Y T R D
Frog Xenopus laevis Q6DCL5 944 106566 Y837 D W M K N T E Y T S G Y E R D
Zebra Danio Brachydanio rerio NP_001007319 857 97523 Y758 A L E E S T E Y D G G Y N K D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 Y845 D W Q R N T I Y R H Y N R N S
Honey Bee Apis mellifera XP_394656 898 100748 Y799 E L E A A T E Y E G G Y T V D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203179 881 99830 Y782 E L E K A T E Y D G G Y T S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40985 892 103438 Y792 S L R S V T K Y V G G F S D D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.5 97.5 N.A. 92.8 26 N.A. 66.9 93.5 22.5 84.5 N.A. 23.6 48.3 N.A. 51.3
Protein Similarity: 100 99 98.9 98.4 N.A. 95.2 43.7 N.A. 73.4 96.5 40.7 90.9 N.A. 41.2 66.5 N.A. 69.2
P-Site Identity: 100 100 100 100 N.A. 93.3 46.6 N.A. 20 100 46.6 80 N.A. 13.3 66.6 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 60 N.A. 20 100 53.3 93.3 N.A. 20 73.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 40 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 8 15 0 0 0 0 0 0 0 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 15 0 0 0 0 0 0 0 58 0 0 0 0 8 65 % D
% Glu: 22 0 72 50 0 0 79 0 8 0 8 0 8 0 15 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 79 79 0 0 0 0 % G
% His: 0 8 0 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 22 0 0 8 0 8 0 0 0 0 8 0 % K
% Leu: 0 79 0 0 0 0 0 0 0 0 0 0 0 0 8 % L
% Met: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 22 0 0 0 0 0 0 8 8 8 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 8 0 0 8 0 8 0 8 0 8 58 0 % R
% Ser: 8 0 0 8 8 0 0 8 0 8 0 8 8 8 8 % S
% Thr: 0 0 8 0 50 93 0 0 8 0 0 0 58 0 8 % T
% Val: 0 0 0 8 8 0 0 0 8 8 0 0 0 8 0 % V
% Trp: 0 15 0 0 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 0 0 0 0 93 8 0 8 79 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _