KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
36.06
Human Site:
Y668
Identified Species:
61.03
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
Y668
S
L
K
D
L
L
E
Y
E
G
N
V
E
D
D
Chimpanzee
Pan troglodytes
XP_510256
879
101065
Y672
S
L
K
D
L
L
E
Y
E
G
N
V
E
D
D
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
Y672
S
L
K
D
L
L
E
Y
E
G
N
V
E
D
D
Dog
Lupus familis
XP_848240
875
100388
Y668
S
L
K
D
L
L
E
Y
E
G
N
V
E
D
D
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
Y678
S
L
K
D
L
L
E
Y
E
G
S
V
E
D
D
Rat
Rattus norvegicus
Q5PQN1
1057
118521
Y851
S
M
Q
Q
L
L
D
Y
P
E
D
D
I
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
N619
N
L
G
L
Y
Y
D
N
R
I
R
M
Y
S
E
Chicken
Gallus gallus
XP_416882
880
100974
Y673
S
L
R
D
L
L
E
Y
E
G
S
V
E
D
D
Frog
Xenopus laevis
Q6DCL5
944
106566
L730
A
K
N
L
Q
W
I
L
D
N
D
I
S
D
L
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
Y650
S
L
K
D
L
M
E
Y
E
G
N
V
E
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
K738
Y
N
S
L
I
W
V
K
D
N
N
I
D
E
C
Honey Bee
Apis mellifera
XP_394656
898
100748
Y690
T
L
K
E
L
M
D
Y
T
G
D
D
M
P
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
H674
S
L
K
A
L
L
E
H
E
D
T
V
E
E
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
Y671
N
L
I
K
M
L
N
Y
T
E
D
N
F
E
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
26.6
N.A.
6.6
86.6
6.6
86.6
N.A.
6.6
40
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
66.6
N.A.
33.3
100
33.3
100
N.A.
40
73.3
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% C
% Asp:
0
0
0
50
0
0
22
0
15
8
29
15
8
50
65
% D
% Glu:
0
0
0
8
0
0
58
0
58
15
0
0
58
36
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
58
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
8
0
8
0
0
8
0
15
8
0
0
% I
% Lys:
0
8
58
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
79
0
22
72
65
0
8
0
0
0
0
0
0
8
% L
% Met:
0
8
0
0
8
15
0
0
0
0
0
8
8
0
0
% M
% Asn:
15
8
8
0
0
0
8
8
0
15
43
8
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
8
0
0
0
0
8
0
% P
% Gln:
0
0
8
8
8
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
8
0
0
0
0
0
8
0
8
0
0
0
0
% R
% Ser:
65
0
8
0
0
0
0
0
0
0
15
0
8
8
0
% S
% Thr:
8
0
0
0
0
0
0
0
15
0
8
0
0
0
8
% T
% Val:
0
0
0
0
0
0
8
0
0
0
0
58
0
0
0
% V
% Trp:
0
0
0
0
0
15
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
0
8
8
0
72
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _