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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
29.39
Human Site:
Y592
Identified Species:
49.74
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
Y592
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Chimpanzee
Pan troglodytes
XP_510256
879
101065
Y596
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
Y596
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Dog
Lupus familis
XP_848240
875
100388
Y592
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
T602
N
P
D
I
G
M
F
T
Y
D
E
A
T
K
L
Rat
Rattus norvegicus
Q5PQN1
1057
118521
Y775
P
K
Y
G
M
F
R
Y
Y
E
D
S
R
L
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
K543
G
E
E
R
R
N
K
K
G
P
R
V
D
P
L
Chicken
Gallus gallus
XP_416882
880
100974
Y597
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Frog
Xenopus laevis
Q6DCL5
944
106566
S654
D
Y
A
L
F
T
Q
S
A
D
G
T
T
F
Q
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
Y574
P
D
I
G
M
F
T
Y
D
E
S
T
K
L
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
N662
Y
C
L
F
E
Y
A
N
K
N
N
Y
S
L
Q
Honey Bee
Apis mellifera
XP_394656
898
100748
T614
P
D
Y
G
M
F
T
T
Q
E
D
T
Q
M
T
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
H598
P
D
I
G
M
F
T
H
N
S
D
L
Q
T
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
F595
K
E
S
S
R
S
W
F
A
I
D
P
P
N
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
0
46.6
N.A.
0
100
6.6
100
N.A.
6.6
53.3
N.A.
46.6
P-Site Similarity:
100
100
100
100
N.A.
6.6
60
N.A.
6.6
100
13.3
100
N.A.
26.6
66.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
0
0
0
8
0
15
0
0
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
58
8
0
0
0
0
0
43
15
29
0
8
0
0
% D
% Glu:
0
15
8
0
8
0
0
0
0
58
8
0
0
0
0
% E
% Phe:
0
0
0
8
8
65
8
8
0
0
0
0
0
8
50
% F
% Gly:
8
0
0
65
8
0
0
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
8
0
0
0
0
0
8
0
0
0
0
8
% I
% Lys:
8
8
0
0
0
0
8
8
8
0
0
0
43
8
0
% K
% Leu:
0
0
8
8
0
0
0
0
0
0
0
8
0
58
15
% L
% Met:
0
0
0
0
65
8
0
0
0
0
0
0
0
8
0
% M
% Asn:
8
0
0
0
0
8
0
8
8
8
8
0
0
8
0
% N
% Pro:
65
8
0
0
0
0
0
0
0
8
0
8
8
8
0
% P
% Gln:
0
0
0
0
0
0
8
0
8
0
0
0
15
0
15
% Q
% Arg:
0
0
0
8
15
0
8
0
0
0
8
0
8
0
0
% R
% Ser:
0
0
8
8
0
8
0
8
0
8
43
8
8
0
0
% S
% Thr:
0
0
0
0
0
8
58
15
0
0
0
58
15
8
8
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
15
0
0
8
0
50
15
0
0
8
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _