KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
29.39
Human Site:
Y301
Identified Species:
49.74
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
Y301
R
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Chimpanzee
Pan troglodytes
XP_510256
879
101065
Y305
R
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
Y305
R
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Dog
Lupus familis
XP_848240
875
100388
Y301
R
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
Y312
S
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Rat
Rattus norvegicus
Q5PQN1
1057
118521
V458
T
G
T
R
F
S
G
V
D
M
N
A
A
R
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
H295
S
F
R
K
A
K
Q
H
T
K
E
E
L
K
S
Chicken
Gallus gallus
XP_416882
880
100974
Y306
G
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Frog
Xenopus laevis
Q6DCL5
944
106566
A385
K
H
T
L
I
Y
Q
A
T
S
E
Q
D
P
L
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
L298
F
C
K
A
M
S
K
L
P
L
P
A
L
A
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
Q358
T
D
P
Q
L
Q
T
Q
P
A
D
D
E
P
L
Honey Bee
Apis mellifera
XP_394656
898
100748
Y337
P
M
L
G
N
S
E
Y
L
E
L
A
L
H
M
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
Y307
P
M
M
S
S
P
E
Y
L
E
V
A
F
P
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
Y314
T
P
T
D
N
F
S
Y
Q
V
E
I
L
N
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
93.3
13.3
N.A.
6.6
93.3
13.3
13.3
N.A.
13.3
46.6
N.A.
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
13.3
N.A.
33.3
93.3
33.3
20
N.A.
20
66.6
N.A.
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
0
0
8
0
8
0
72
8
8
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
0
8
0
0
0
0
8
0
8
8
8
0
0
% D
% Glu:
0
0
0
0
0
0
58
0
0
58
22
8
8
0
0
% E
% Phe:
8
8
0
0
8
8
0
0
0
0
0
0
8
0
0
% F
% Gly:
8
8
0
8
0
0
8
0
0
0
0
0
0
0
0
% G
% His:
0
8
0
43
0
0
0
8
0
0
0
0
0
8
0
% H
% Ile:
0
0
0
0
8
0
0
0
0
0
0
8
0
0
0
% I
% Lys:
8
0
8
8
0
8
8
0
0
8
0
0
0
8
8
% K
% Leu:
0
0
50
8
8
0
0
8
58
8
8
0
72
0
72
% L
% Met:
0
15
8
0
8
0
0
0
0
8
43
0
0
0
8
% M
% Asn:
0
43
0
0
15
0
0
0
0
0
8
0
0
8
0
% N
% Pro:
15
8
8
0
0
50
0
0
15
0
8
0
0
65
0
% P
% Gln:
0
0
0
8
0
8
15
8
8
0
0
8
0
0
0
% Q
% Arg:
29
0
8
8
0
0
0
0
0
0
0
0
0
8
0
% R
% Ser:
15
0
0
8
50
22
8
0
0
8
0
0
0
0
8
% S
% Thr:
22
0
22
0
0
0
8
0
15
0
0
0
0
0
8
% T
% Val:
0
0
0
0
0
0
0
8
0
8
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
65
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _