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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3A All Species: 38.18
Human Site: T834 Identified Species: 64.62
UniProt: Q05086 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05086 NP_000453.2 875 100688 T834 I A K N G P D T E R L P T S H
Chimpanzee Pan troglodytes XP_510256 879 101065 T838 I A K N G P D T E R L P T S H
Rhesus Macaque Macaca mulatta XP_001108510 879 101081 T838 I A K N G P D T E R L P T S H
Dog Lupus familis XP_848240 875 100388 T834 I A K N G P D T E R L P T S H
Cat Felis silvestris
Mouse Mus musculus O08759 885 101157 T844 I A K N G P D T E R L P T S H
Rat Rattus norvegicus Q5PQN1 1057 118521 E1016 I Q S T G G G E S Y L P V S H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514205 825 94298 F785 A D A N L P S F G R L L A R A
Chicken Gallus gallus XP_416882 880 100974 T839 I A K N G P D T E R L P T S H
Frog Xenopus laevis Q6DCL5 944 106566 A902 I A A V A Y T A N L L P T S S
Zebra Danio Brachydanio rerio NP_001007319 857 97523 S816 I A K N G P D S D R L P T S H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 E908 C I E K V G K E T W L P R S H
Honey Bee Apis mellifera XP_394656 898 100748 S857 I A R H G P D S D R L P I A H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203179 881 99830 S840 L A K N G P D S D R L P T S H
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40985 892 103438 S851 S L L G S H D S D D L P L A H
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.5 97.5 N.A. 92.8 26 N.A. 66.9 93.5 22.5 84.5 N.A. 23.6 48.3 N.A. 51.3
Protein Similarity: 100 99 98.9 98.4 N.A. 95.2 43.7 N.A. 73.4 96.5 40.7 90.9 N.A. 41.2 66.5 N.A. 69.2
P-Site Identity: 100 100 100 100 N.A. 100 40 N.A. 26.6 100 40 86.6 N.A. 26.6 60 N.A. 80
P-Site Similarity: 100 100 100 100 N.A. 100 40 N.A. 26.6 100 40 100 N.A. 33.3 93.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 26.6 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 72 15 0 8 0 0 8 0 0 0 0 8 15 8 % A
% Cys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 72 0 29 8 0 0 0 0 0 % D
% Glu: 0 0 8 0 0 0 0 15 43 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 8 72 15 8 0 8 0 0 0 0 0 0 % G
% His: 0 0 0 8 0 8 0 0 0 0 0 0 0 0 86 % H
% Ile: 72 8 0 0 0 0 0 0 0 0 0 0 8 0 0 % I
% Lys: 0 0 58 8 0 0 8 0 0 0 0 0 0 0 0 % K
% Leu: 8 8 8 0 8 0 0 0 0 8 100 8 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 65 0 0 0 0 8 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 72 0 0 0 0 0 93 0 0 0 % P
% Gln: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 8 0 0 0 0 0 0 72 0 0 8 8 0 % R
% Ser: 8 0 8 0 8 0 8 29 8 0 0 0 0 79 8 % S
% Thr: 0 0 0 8 0 0 8 43 8 0 0 0 65 0 0 % T
% Val: 0 0 0 8 8 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 0 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _