Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3A All Species: 29.39
Human Site: T591 Identified Species: 49.74
UniProt: Q05086 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05086 NP_000453.2 875 100688 T591 N P D I G M F T Y D E S T K L
Chimpanzee Pan troglodytes XP_510256 879 101065 T595 N P D I G M F T Y D E S T K L
Rhesus Macaque Macaca mulatta XP_001108510 879 101081 T595 N P D I G M F T Y D E S T K L
Dog Lupus familis XP_848240 875 100388 T591 N P D I G M F T Y D E S T K L
Cat Felis silvestris
Mouse Mus musculus O08759 885 101157 F601 F N P D I G M F T Y D E A T K
Rat Rattus norvegicus Q5PQN1 1057 118521 R774 D P K Y G M F R Y Y E D S R L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514205 825 94298 K542 L G E E R R N K K G P R V D P
Chicken Gallus gallus XP_416882 880 100974 T596 N P D I G M F T Y D E S T K L
Frog Xenopus laevis Q6DCL5 944 106566 Q653 P D Y A L F T Q S A D G T T F
Zebra Danio Brachydanio rerio NP_001007319 857 97523 T573 N P D I G M F T Y D E S T K L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 A661 M Y C L F E Y A N K N N Y S L
Honey Bee Apis mellifera XP_394656 898 100748 T613 N P D Y G M F T T Q E D T Q M
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203179 881 99830 T597 N P D I G M F T H N S D L Q T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40985 892 103438 W594 I K E S S R S W F A I D P P N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.5 97.5 N.A. 92.8 26 N.A. 66.9 93.5 22.5 84.5 N.A. 23.6 48.3 N.A. 51.3
Protein Similarity: 100 99 98.9 98.4 N.A. 95.2 43.7 N.A. 73.4 96.5 40.7 90.9 N.A. 41.2 66.5 N.A. 69.2
P-Site Identity: 100 100 100 100 N.A. 0 46.6 N.A. 0 100 6.6 100 N.A. 6.6 60 N.A. 53.3
P-Site Similarity: 100 100 100 100 N.A. 6.6 66.6 N.A. 6.6 100 13.3 100 N.A. 26.6 73.3 N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 8 0 15 0 0 8 0 0 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 8 58 8 0 0 0 0 0 43 15 29 0 8 0 % D
% Glu: 0 0 15 8 0 8 0 0 0 0 58 8 0 0 0 % E
% Phe: 8 0 0 0 8 8 65 8 8 0 0 0 0 0 8 % F
% Gly: 0 8 0 0 65 8 0 0 0 8 0 8 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % H
% Ile: 8 0 0 50 8 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 0 8 8 0 0 0 0 8 8 8 0 0 0 43 8 % K
% Leu: 8 0 0 8 8 0 0 0 0 0 0 0 8 0 58 % L
% Met: 8 0 0 0 0 65 8 0 0 0 0 0 0 0 8 % M
% Asn: 58 8 0 0 0 0 8 0 8 8 8 8 0 0 8 % N
% Pro: 8 65 8 0 0 0 0 0 0 0 8 0 8 8 8 % P
% Gln: 0 0 0 0 0 0 0 8 0 8 0 0 0 15 0 % Q
% Arg: 0 0 0 0 8 15 0 8 0 0 0 8 0 8 0 % R
% Ser: 0 0 0 8 8 0 8 0 8 0 8 43 8 8 0 % S
% Thr: 0 0 0 0 0 0 8 58 15 0 0 0 58 15 8 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % V
% Trp: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % W
% Tyr: 0 8 8 15 0 0 8 0 50 15 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _