KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
26.67
Human Site:
T436
Identified Species:
45.13
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
T436
E
T
E
L
G
V
K
T
L
D
C
R
K
P
L
Chimpanzee
Pan troglodytes
XP_510256
879
101065
T440
E
T
E
L
G
V
K
T
L
D
C
R
K
P
L
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
T440
E
T
E
L
G
V
K
T
L
D
C
R
K
P
L
Dog
Lupus familis
XP_848240
875
100388
T436
E
T
E
L
G
V
K
T
L
D
C
R
K
P
L
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
T447
E
T
E
L
G
V
K
T
L
D
C
R
K
P
L
Rat
Rattus norvegicus
Q5PQN1
1057
118521
T607
L
H
R
V
N
E
R
T
G
Q
L
I
Q
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
Y423
G
N
L
H
S
P
E
Y
L
E
M
A
L
P
L
Chicken
Gallus gallus
XP_416882
880
100974
T441
E
T
E
L
G
V
K
T
I
D
C
R
K
P
L
Frog
Xenopus laevis
Q6DCL5
944
106566
F514
T
S
P
R
F
I
E
F
V
C
K
H
D
E
V
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
E429
R
K
P
L
I
P
F
E
E
F
I
N
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
F495
Q
S
D
N
R
V
Y
F
V
N
H
K
N
R
T
Honey Bee
Apis mellifera
XP_394656
898
100748
T470
R
K
P
F
I
P
F
T
D
F
Y
N
E
P
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
V442
A
K
K
L
G
L
T
V
L
D
C
R
K
P
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
D444
D
F
I
D
Y
K
Q
D
F
D
H
W
R
G
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
100
6.6
N.A.
20
93.3
0
20
N.A.
6.6
20
N.A.
60
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
33.3
100
33.3
26.6
N.A.
46.6
26.6
N.A.
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
50
0
0
0
0
% C
% Asp:
8
0
8
8
0
0
0
8
8
58
0
0
8
0
8
% D
% Glu:
43
0
43
0
0
8
15
8
8
8
0
0
15
8
0
% E
% Phe:
0
8
0
8
8
0
15
15
8
15
0
0
0
0
0
% F
% Gly:
8
0
0
0
50
0
0
0
8
0
0
0
0
8
0
% G
% His:
0
8
0
8
0
0
0
0
0
0
15
8
0
0
0
% H
% Ile:
0
0
8
0
15
8
0
0
8
0
8
8
0
0
0
% I
% Lys:
0
22
8
0
0
8
43
0
0
0
8
8
50
0
0
% K
% Leu:
8
0
8
58
0
8
0
0
50
0
8
0
8
0
72
% L
% Met:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% M
% Asn:
0
8
0
8
8
0
0
0
0
8
0
15
8
0
0
% N
% Pro:
0
0
22
0
0
22
0
0
0
0
0
0
0
72
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
8
0
0
8
0
0
% Q
% Arg:
15
0
8
8
8
0
8
0
0
0
0
50
8
8
0
% R
% Ser:
0
15
0
0
8
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
8
43
0
0
0
0
8
58
0
0
0
0
0
0
8
% T
% Val:
0
0
0
8
0
50
0
8
15
0
0
0
0
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
8
8
0
0
8
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _