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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
19.09
Human Site:
T126
Identified Species:
32.31
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
T126
R
I
D
F
K
D
V
T
Y
L
T
E
E
K
V
Chimpanzee
Pan troglodytes
XP_510256
879
101065
T130
R
I
D
F
K
D
V
T
Y
L
T
E
E
K
V
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
T130
R
I
D
F
K
D
V
T
Y
L
T
E
E
K
V
Dog
Lupus familis
XP_848240
875
100388
T127
R
D
D
F
R
D
V
T
Y
L
T
E
E
T
V
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
I137
G
K
D
F
K
D
V
I
Y
L
T
E
E
K
V
Rat
Rattus norvegicus
Q5PQN1
1057
118521
K132
I
R
V
P
R
N
I
K
S
L
S
D
I
Q
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
N124
A
D
L
S
A
K
R
N
Q
E
R
L
K
Q
T
Chicken
Gallus gallus
XP_416882
880
100974
T128
R
D
D
F
K
D
V
T
F
L
T
E
D
K
I
Frog
Xenopus laevis
Q6DCL5
944
106566
D211
A
C
S
H
G
Q
R
D
T
A
Q
I
L
L
L
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
C122
V
Y
E
I
L
S
I
C
S
E
T
E
D
Y
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
N173
G
E
L
V
A
I
L
N
G
L
K
L
D
M
S
Honey Bee
Apis mellifera
XP_394656
898
100748
P165
I
S
Q
R
K
Q
D
P
Y
L
T
E
A
K
L
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
S134
P
L
D
T
Q
R
S
S
S
E
S
D
S
I
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
D142
M
V
V
R
R
C
H
D
D
L
Q
R
L
K
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
80
N.A.
80
6.6
N.A.
0
73.3
0
13.3
N.A.
6.6
40
N.A.
6.6
P-Site Similarity:
100
100
100
86.6
N.A.
80
53.3
N.A.
13.3
93.3
6.6
33.3
N.A.
20
46.6
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
0
0
15
0
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
8
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
22
50
0
0
43
8
15
8
0
0
15
22
0
0
% D
% Glu:
0
8
8
0
0
0
0
0
0
22
0
58
36
0
0
% E
% Phe:
0
0
0
43
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
15
0
0
0
8
0
0
0
8
0
0
0
0
0
0
% G
% His:
0
0
0
8
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
15
22
0
8
0
8
15
8
0
0
0
8
8
8
15
% I
% Lys:
0
8
0
0
43
8
0
8
0
0
8
0
8
50
15
% K
% Leu:
0
8
15
0
8
0
8
0
0
72
0
15
15
8
15
% L
% Met:
8
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
8
0
15
0
0
0
0
0
0
0
% N
% Pro:
8
0
0
8
0
0
0
8
0
0
0
0
0
0
0
% P
% Gln:
0
0
8
0
8
15
0
0
8
0
15
0
0
15
0
% Q
% Arg:
36
8
0
15
22
8
15
0
0
0
8
8
0
0
0
% R
% Ser:
0
8
8
8
0
8
8
8
22
0
15
0
8
0
15
% S
% Thr:
0
0
0
8
0
0
0
36
8
0
58
0
0
8
8
% T
% Val:
8
8
15
8
0
0
43
0
0
0
0
0
0
0
36
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
43
0
0
0
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _