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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3A All Species: 40.3
Human Site: S840 Identified Species: 68.21
UniProt: Q05086 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05086 NP_000453.2 875 100688 S840 D T E R L P T S H T C F N V L
Chimpanzee Pan troglodytes XP_510256 879 101065 S844 D T E R L P T S H T C F N V L
Rhesus Macaque Macaca mulatta XP_001108510 879 101081 S844 D T E R L P T S H T C F N V L
Dog Lupus familis XP_848240 875 100388 S840 D T E R L P T S H T C F N V L
Cat Felis silvestris
Mouse Mus musculus O08759 885 101157 S850 D T E R L P T S H T C F N V L
Rat Rattus norvegicus Q5PQN1 1057 118521 S1022 G E S Y L P V S H T C F N L L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514205 825 94298 R791 S F G R L L A R A R L R W E R
Chicken Gallus gallus XP_416882 880 100974 S845 D T E R L P T S H T C F N V L
Frog Xenopus laevis Q6DCL5 944 106566 S908 T A N L L P T S S T C I N M L
Zebra Danio Brachydanio rerio NP_001007319 857 97523 S822 D S D R L P T S H T C F N V L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 S914 K E T W L P R S H T C F N R L
Honey Bee Apis mellifera XP_394656 898 100748 A863 D S D R L P I A H T C Y N V L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203179 881 99830 S846 D S D R L P T S H T C F N V L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40985 892 103438 A857 D S D D L P L A H T C F N E I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.5 97.5 N.A. 92.8 26 N.A. 66.9 93.5 22.5 84.5 N.A. 23.6 48.3 N.A. 51.3
Protein Similarity: 100 99 98.9 98.4 N.A. 95.2 43.7 N.A. 73.4 96.5 40.7 90.9 N.A. 41.2 66.5 N.A. 69.2
P-Site Identity: 100 100 100 100 N.A. 100 60 N.A. 13.3 100 53.3 86.6 N.A. 60 66.6 N.A. 86.6
P-Site Similarity: 100 100 100 100 N.A. 100 66.6 N.A. 13.3 100 60 100 N.A. 60 93.3 N.A. 100
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 0 0 8 15 8 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 93 0 0 0 0 % C
% Asp: 72 0 29 8 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 15 43 0 0 0 0 0 0 0 0 0 0 15 0 % E
% Phe: 0 8 0 0 0 0 0 0 0 0 0 79 0 0 0 % F
% Gly: 8 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 86 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % I
% Lys: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 8 100 8 8 0 0 0 8 0 0 8 86 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 8 0 % M
% Asn: 0 0 8 0 0 0 0 0 0 0 0 0 93 0 0 % N
% Pro: 0 0 0 0 0 93 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 72 0 0 8 8 0 8 0 8 0 8 8 % R
% Ser: 8 29 8 0 0 0 0 79 8 0 0 0 0 0 0 % S
% Thr: 8 43 8 0 0 0 65 0 0 93 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 65 0 % V
% Trp: 0 0 0 8 0 0 0 0 0 0 0 0 8 0 0 % W
% Tyr: 0 0 0 8 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _