KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
17.88
Human Site:
S248
Identified Species:
30.26
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
S248
R
V
Y
T
R
L
L
S
N
E
K
I
E
T
A
Chimpanzee
Pan troglodytes
XP_510256
879
101065
S252
R
V
Y
T
R
L
L
S
N
E
K
I
E
T
A
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
S252
R
V
Y
T
R
L
L
S
N
E
K
I
E
T
A
Dog
Lupus familis
XP_848240
875
100388
S248
R
V
Y
T
R
L
L
S
N
E
K
I
E
T
A
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
A259
R
V
Y
S
S
L
L
A
N
E
K
L
E
T
A
Rat
Rattus norvegicus
Q5PQN1
1057
118521
A405
Q
I
W
T
V
N
E
A
L
I
Q
K
W
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
D242
K
E
A
H
G
P
R
D
D
F
K
D
V
T
Y
Chicken
Gallus gallus
XP_416882
880
100974
S253
R
V
Y
D
R
L
L
S
N
E
K
I
E
T
A
Frog
Xenopus laevis
Q6DCL5
944
106566
R332
R
I
F
C
H
V
F
R
I
G
P
S
S
P
N
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
L245
F
L
N
A
L
V
Y
L
S
P
N
V
E
C
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
V305
L
A
R
P
L
T
Q
V
Y
G
A
L
P
E
N
Honey Bee
Apis mellifera
XP_394656
898
100748
E284
A
L
W
S
L
P
G
E
V
F
K
S
A
L
V
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
D254
Y
E
A
I
T
K
L
D
E
E
R
V
N
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
R261
T
I
R
T
C
L
I
R
D
R
K
S
K
N
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
100
N.A.
73.3
6.6
N.A.
13.3
93.3
6.6
6.6
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
93.3
46.6
N.A.
26.6
93.3
26.6
33.3
N.A.
6.6
26.6
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
15
8
0
0
0
15
0
0
8
0
8
0
50
% A
% Cys:
0
0
0
8
8
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
0
0
0
15
15
0
0
8
0
0
8
% D
% Glu:
0
15
0
0
0
0
8
8
8
50
0
0
50
8
0
% E
% Phe:
8
0
8
0
0
0
8
0
0
15
0
0
0
0
0
% F
% Gly:
0
0
0
0
8
0
8
0
0
15
0
0
0
0
0
% G
% His:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
22
0
8
0
0
8
0
8
8
0
36
0
0
0
% I
% Lys:
8
0
0
0
0
8
0
0
0
0
65
8
8
0
0
% K
% Leu:
8
15
0
0
22
50
50
8
8
0
0
15
0
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
43
0
8
0
8
15
15
% N
% Pro:
0
0
0
8
0
15
0
0
0
8
8
0
8
8
0
% P
% Gln:
8
0
0
0
0
0
8
0
0
0
8
0
0
0
0
% Q
% Arg:
50
0
15
0
36
0
8
15
0
8
8
0
0
0
0
% R
% Ser:
0
0
0
15
8
0
0
36
8
0
0
22
8
0
8
% S
% Thr:
8
0
0
43
8
8
0
0
0
0
0
0
0
50
0
% T
% Val:
0
43
0
0
8
15
0
8
8
0
0
15
8
0
15
% V
% Trp:
0
0
15
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
8
0
43
0
0
0
8
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _