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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
20.3
Human Site:
S207
Identified Species:
34.36
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
S207
A
A
A
M
E
E
D
S
E
A
S
S
S
R
I
Chimpanzee
Pan troglodytes
XP_510256
879
101065
S211
A
A
A
M
E
E
D
S
E
A
S
S
S
R
I
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
S211
A
A
A
M
E
E
D
S
E
A
S
S
S
R
I
Dog
Lupus familis
XP_848240
875
100388
S207
S
A
A
M
E
E
D
S
E
A
S
S
S
R
I
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
S218
A
A
A
M
E
E
D
S
E
A
S
S
S
R
M
Rat
Rattus norvegicus
Q5PQN1
1057
118521
V364
G
S
E
D
Y
F
C
V
K
R
I
F
S
G
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
C201
Y
K
I
N
A
K
L
C
D
P
H
P
S
K
K
Chicken
Gallus gallus
XP_416882
880
100974
S212
M
E
E
D
S
G
A
S
S
S
S
S
S
R
I
Frog
Xenopus laevis
Q6DCL5
944
106566
I291
S
E
V
Q
Y
L
K
I
L
T
G
L
A
E
V
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
N204
D
G
S
S
H
G
E
N
N
V
Q
K
L
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
Q264
P
V
W
E
Q
Q
Q
Q
Q
S
Q
N
Q
Q
Q
Honey Bee
Apis mellifera
XP_394656
898
100748
Q243
K
E
A
I
R
S
I
Q
G
E
D
K
E
E
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
L213
T
D
E
M
D
E
G
L
Q
S
I
S
T
R
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
L220
R
K
P
Y
Y
S
M
L
C
C
C
N
D
L
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
93.3
N.A.
93.3
6.6
N.A.
6.6
40
0
0
N.A.
0
6.6
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
100
20
N.A.
26.6
46.6
20
20
N.A.
40
13.3
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
29
36
43
0
8
0
8
0
0
36
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
8
8
8
8
8
0
0
0
0
% C
% Asp:
8
8
0
15
8
0
36
0
8
0
8
0
8
0
8
% D
% Glu:
0
22
22
8
36
43
8
0
36
8
0
0
8
15
0
% E
% Phe:
0
0
0
0
0
8
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
8
0
0
0
15
8
0
8
0
8
0
0
15
8
% G
% His:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
8
8
0
0
15
0
0
0
36
% I
% Lys:
8
15
0
0
0
8
8
0
8
0
0
15
0
8
8
% K
% Leu:
0
0
0
0
0
8
8
15
8
0
0
8
8
8
15
% L
% Met:
8
0
0
43
0
0
8
0
0
0
0
0
0
0
8
% M
% Asn:
0
0
0
8
0
0
0
8
8
0
0
15
0
0
0
% N
% Pro:
8
0
8
0
0
0
0
0
0
8
0
8
0
0
8
% P
% Gln:
0
0
0
8
8
8
8
15
15
0
15
0
8
8
8
% Q
% Arg:
8
0
0
0
8
0
0
0
0
8
0
0
0
50
0
% R
% Ser:
15
8
8
8
8
15
0
43
8
22
43
50
58
0
0
% S
% Thr:
8
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% T
% Val:
0
8
8
0
0
0
0
8
0
8
0
0
0
0
8
% V
% Trp:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
0
0
8
22
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _