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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
25.76
Human Site:
S180
Identified Species:
43.59
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
S180
H
T
K
E
E
L
K
S
L
Q
A
K
D
E
D
Chimpanzee
Pan troglodytes
XP_510256
879
101065
S184
H
T
K
E
E
L
K
S
L
Q
A
K
D
E
D
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
S184
H
T
K
E
E
L
K
S
L
Q
A
K
D
E
D
Dog
Lupus familis
XP_848240
875
100388
S181
H
T
K
E
E
L
K
S
L
Q
G
K
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
S191
H
T
K
D
E
L
K
S
L
Q
E
K
D
E
D
Rat
Rattus norvegicus
Q5PQN1
1057
118521
S186
T
S
P
Q
L
I
K
S
L
L
G
I
P
F
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
F178
F
C
A
S
C
P
T
F
L
R
L
D
N
N
A
Chicken
Gallus gallus
XP_416882
880
100974
S182
H
T
K
E
E
L
K
S
L
Q
G
K
D
E
D
Frog
Xenopus laevis
Q6DCL5
944
106566
N265
T
L
I
Q
M
T
Q
N
E
E
L
R
E
N
M
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
E176
D
K
D
E
D
E
K
E
T
A
S
G
S
S
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
R227
V
R
A
R
M
R
L
R
S
S
S
G
N
S
N
Honey Bee
Apis mellifera
XP_394656
898
100748
L219
N
D
S
P
L
A
A
L
L
D
R
A
S
D
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
T188
L
N
K
S
F
L
R
T
V
K
Q
G
L
S
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
N196
G
K
N
I
K
M
L
N
Y
E
V
L
Q
R
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
93.3
N.A.
86.6
20
N.A.
6.6
93.3
0
13.3
N.A.
0
6.6
N.A.
20
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
40
N.A.
20
93.3
40
26.6
N.A.
20
20
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
8
8
0
0
8
22
8
0
0
8
% A
% Cys:
0
8
0
0
8
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
8
8
8
8
0
0
0
0
8
0
8
43
8
50
% D
% Glu:
0
0
0
43
43
8
0
8
8
15
8
0
8
43
0
% E
% Phe:
8
0
0
0
8
0
0
8
0
0
0
0
0
8
8
% F
% Gly:
8
0
0
0
0
0
0
0
0
0
22
22
0
0
0
% G
% His:
43
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
8
0
0
0
0
0
8
0
0
0
% I
% Lys:
0
15
50
0
8
0
58
0
0
8
0
43
0
0
0
% K
% Leu:
8
8
0
0
15
50
15
8
65
8
15
8
8
0
0
% L
% Met:
0
0
0
0
15
8
0
0
0
0
0
0
0
0
15
% M
% Asn:
8
8
8
0
0
0
0
15
0
0
0
0
15
15
8
% N
% Pro:
0
0
8
8
0
8
0
0
0
0
0
0
8
0
0
% P
% Gln:
0
0
0
15
0
0
8
0
0
43
8
0
8
0
0
% Q
% Arg:
0
8
0
8
0
8
8
8
0
8
8
8
0
8
0
% R
% Ser:
0
8
8
15
0
0
0
50
8
8
15
0
15
22
8
% S
% Thr:
15
43
0
0
0
8
8
8
8
0
0
0
0
0
8
% T
% Val:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _