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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: UBE3A All Species: 15.15
Human Site: S16 Identified Species: 25.64
UniProt: Q05086 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q05086 NP_000453.2 875 100688 S16 W K S G E P Q S D D I E A S R
Chimpanzee Pan troglodytes XP_510256 879 101065 S20 Y R S G E P Q S D D I E A S R
Rhesus Macaque Macaca mulatta XP_001108510 879 101081 S20 Y R S G E P Q S D D I E A S R
Dog Lupus familis XP_848240 875 100388 D16 P G E P Q S D D I E A S R M K
Cat Felis silvestris
Mouse Mus musculus O08759 885 101157 S30 S S P G E S Q S E D I E A S R
Rat Rattus norvegicus Q5PQN1 1057 118521 I17 G Q L G L G G I D E E I V L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514205 825 94298 E17 E D L G H S R E N P F D Q S G
Chicken Gallus gallus XP_416882 880 100974 N16 P G E P H S E N I E T S R M K
Frog Xenopus laevis Q6DCL5 944 106566 L23 R R A R T V E L P E D N E T A
Zebra Danio Brachydanio rerio NP_001007319 857 97523 Q16 L I E R Y Y H Q L T E G C G N
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9Y0H4 949 107948 S27 Q T V N G A G S A S P T P T S
Honey Bee Apis mellifera XP_394656 898 100748 G18 E D H A S R G G A K S P C S D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001203179 881 99830 Y24 A R G L I E R Y F Y Q L T N G
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40985 892 103438 S27 S K E L L S H S V A H T K N R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 98.5 97.5 N.A. 92.8 26 N.A. 66.9 93.5 22.5 84.5 N.A. 23.6 48.3 N.A. 51.3
Protein Similarity: 100 99 98.9 98.4 N.A. 95.2 43.7 N.A. 73.4 96.5 40.7 90.9 N.A. 41.2 66.5 N.A. 69.2
P-Site Identity: 100 86.6 86.6 0 N.A. 66.6 13.3 N.A. 13.3 0 0 0 N.A. 6.6 6.6 N.A. 0
P-Site Similarity: 100 100 100 20 N.A. 73.3 26.6 N.A. 33.3 26.6 33.3 0 N.A. 13.3 6.6 N.A. 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.1 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 0 8 8 0 8 0 0 15 8 8 0 29 0 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 15 0 0 % C
% Asp: 0 15 0 0 0 0 8 8 29 29 8 8 0 0 8 % D
% Glu: 15 0 29 0 29 8 15 8 8 29 15 29 8 0 8 % E
% Phe: 0 0 0 0 0 0 0 0 8 0 8 0 0 0 0 % F
% Gly: 8 15 8 43 8 8 22 8 0 0 0 8 0 8 15 % G
% His: 0 0 8 0 15 0 15 0 0 0 8 0 0 0 0 % H
% Ile: 0 8 0 0 8 0 0 8 15 0 29 8 0 0 0 % I
% Lys: 0 15 0 0 0 0 0 0 0 8 0 0 8 0 15 % K
% Leu: 8 0 15 15 15 0 0 8 8 0 0 8 0 8 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % M
% Asn: 0 0 0 8 0 0 0 8 8 0 0 8 0 15 8 % N
% Pro: 15 0 8 15 0 22 0 0 8 8 8 8 8 0 0 % P
% Gln: 8 8 0 0 8 0 29 8 0 0 8 0 8 0 0 % Q
% Arg: 8 29 0 15 0 8 15 0 0 0 0 0 15 0 36 % R
% Ser: 15 8 22 0 8 36 0 43 0 8 8 15 0 43 8 % S
% Thr: 0 8 0 0 8 0 0 0 0 8 8 15 8 15 0 % T
% Val: 0 0 8 0 0 8 0 0 8 0 0 0 8 0 0 % V
% Trp: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 15 0 0 0 8 8 0 8 0 8 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _