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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
UBE3A
All Species:
18.79
Human Site:
S107
Identified Species:
31.79
UniProt:
Q05086
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q05086
NP_000453.2
875
100688
S107
S
K
G
A
P
N
N
S
C
S
E
I
K
M
N
Chimpanzee
Pan troglodytes
XP_510256
879
101065
S111
S
K
G
A
P
N
N
S
C
S
E
I
K
M
N
Rhesus Macaque
Macaca mulatta
XP_001108510
879
101081
S111
S
K
G
A
P
N
N
S
C
S
E
I
K
M
N
Dog
Lupus familis
XP_848240
875
100388
S105
S
K
G
A
P
N
N
S
C
S
D
I
K
M
N
Cat
Felis silvestris
Mouse
Mus musculus
O08759
885
101157
N119
E
N
S
K
G
A
S
N
N
S
E
I
K
M
N
Rat
Rattus norvegicus
Q5PQN1
1057
118521
L110
G
Q
V
Y
A
W
G
L
D
S
D
G
Q
L
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514205
825
94298
R107
T
A
R
R
R
H
G
R
K
P
L
Y
R
R
G
Chicken
Gallus gallus
XP_416882
880
100974
N105
N
S
K
G
A
H
N
N
S
C
T
D
R
K
M
Frog
Xenopus laevis
Q6DCL5
944
106566
H169
A
M
G
Q
T
A
L
H
V
A
C
Q
N
G
H
Zebra Danio
Brachydanio rerio
NP_001007319
857
97523
R105
P
P
T
R
E
D
F
R
D
L
N
F
L
T
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9Y0H4
949
107948
S118
F
K
V
L
D
H
S
S
F
R
K
D
A
M
L
Honey Bee
Apis mellifera
XP_394656
898
100748
L109
P
A
S
L
A
K
S
L
P
V
K
S
V
N
P
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203179
881
99830
S116
N
T
P
S
T
S
S
S
D
G
D
K
Q
T
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40985
892
103438
S122
E
I
N
S
N
L
E
S
S
T
H
I
S
C
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
98.5
97.5
N.A.
92.8
26
N.A.
66.9
93.5
22.5
84.5
N.A.
23.6
48.3
N.A.
51.3
Protein Similarity:
100
99
98.9
98.4
N.A.
95.2
43.7
N.A.
73.4
96.5
40.7
90.9
N.A.
41.2
66.5
N.A.
69.2
P-Site Identity:
100
100
100
93.3
N.A.
40
6.6
N.A.
0
6.6
6.6
0
N.A.
20
0
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
53.3
33.3
N.A.
20
33.3
26.6
6.6
N.A.
40
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.1
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
29
22
15
0
0
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
29
8
8
0
0
8
0
% C
% Asp:
0
0
0
0
8
8
0
0
22
0
22
15
0
0
0
% D
% Glu:
15
0
0
0
8
0
8
0
0
0
29
0
0
0
8
% E
% Phe:
8
0
0
0
0
0
8
0
8
0
0
8
0
0
0
% F
% Gly:
8
0
36
8
8
0
15
0
0
8
0
8
0
8
15
% G
% His:
0
0
0
0
0
22
0
8
0
0
8
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
43
0
0
0
% I
% Lys:
0
36
8
8
0
8
0
0
8
0
15
8
36
8
0
% K
% Leu:
0
0
0
15
0
8
8
15
0
8
8
0
8
8
15
% L
% Met:
0
8
0
0
0
0
0
0
0
0
0
0
0
43
8
% M
% Asn:
15
8
8
0
8
29
36
15
8
0
8
0
8
8
36
% N
% Pro:
15
8
8
0
29
0
0
0
8
8
0
0
0
0
8
% P
% Gln:
0
8
0
8
0
0
0
0
0
0
0
8
15
0
0
% Q
% Arg:
0
0
8
15
8
0
0
15
0
8
0
0
15
8
0
% R
% Ser:
29
8
15
15
0
8
29
50
15
43
0
8
8
0
0
% S
% Thr:
8
8
8
0
15
0
0
0
0
8
8
0
0
15
8
% T
% Val:
0
0
15
0
0
0
0
0
8
8
0
0
8
0
0
% V
% Trp:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
0
0
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _