Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TLE2 All Species: 36.06
Human Site: S635 Identified Species: 72.12
UniProt: Q04725 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04725 NP_001138233.1 743 79841 S635 D F S S Q I F S L G H C P N Q
Chimpanzee Pan troglodytes XP_512979 739 79294 Q631 Q Q H D F S S Q I F S L G H C
Rhesus Macaque Macaca mulatta XP_001102218 778 84646 S670 D F T S Q I F S L G Y C P T G
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q9WVB2 767 82604 S659 D F S S Q I F S L G H C P N Q
Rat Rattus norvegicus Q9JIT3 764 82625 S656 D F T S Q I F S L G Y C P T G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511916 767 82978 S659 D F T S Q I F S L G Y C P T G
Chicken Gallus gallus NP_989568 773 83801 S665 D F T S Q I F S L G Y C P T G
Frog Xenopus laevis O42478 772 83688 S664 D F T S Q I F S L G Y C P T G
Zebra Danio Brachydanio rerio O13166 761 82441 S653 D F A S Q I F S L G Y C P T G
Tiger Blowfish Takifugu rubipres NP_001032949 763 82638 S655 D F T S Q I F S L G Y C P T G
Fruit Fly Dros. melanogaster P16371 730 80213 S622 D F S S Q I F S L G Y C P T G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans O02482 612 65598 G506 A S Q V F S L G C C P N D E W
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.9 66.1 N.A. N.A. 88.7 67.9 N.A. 68.1 67.2 67 64.1 67.1 55 N.A. 38.6 N.A.
Protein Similarity: 100 97.3 78.2 N.A. N.A. 92.6 79.3 N.A. 79.2 78.5 78.6 75.3 78.7 66.6 N.A. 53.4 N.A.
P-Site Identity: 100 0 73.3 N.A. N.A. 100 73.3 N.A. 73.3 73.3 73.3 73.3 73.3 80 N.A. 0 N.A.
P-Site Similarity: 100 13.3 86.6 N.A. N.A. 100 86.6 N.A. 86.6 86.6 86.6 86.6 86.6 86.6 N.A. 0 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 9 9 0 84 0 0 9 % C
% Asp: 84 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % E
% Phe: 0 84 0 0 17 0 84 0 0 9 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 9 0 84 0 0 9 0 67 % G
% His: 0 0 9 0 0 0 0 0 0 0 17 0 0 9 0 % H
% Ile: 0 0 0 0 0 84 0 0 9 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 9 0 84 0 0 9 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 9 0 17 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 9 0 84 0 0 % P
% Gln: 9 9 9 0 84 0 0 9 0 0 0 0 0 0 17 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 9 25 84 0 17 9 84 0 0 9 0 0 0 0 % S
% Thr: 0 0 50 0 0 0 0 0 0 0 0 0 0 67 0 % T
% Val: 0 0 0 9 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 67 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _