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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
16.06
Human Site:
Y321
Identified Species:
32.12
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
Y321
N
R
S
A
I
V
K
Y
N
A
S
S
V
T
P
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
L261
R
N
V
V
T
L
Q
L
R
I
D
G
M
H
C
Dog
Lupus familis
XP_549096
1499
164030
Y321
N
R
S
A
I
V
K
Y
N
A
S
L
V
T
P
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
Y321
N
R
S
A
I
V
K
Y
N
A
S
L
V
T
P
Rat
Rattus norvegicus
P70705
1492
162074
Y321
N
R
S
A
I
V
K
Y
N
A
S
L
V
T
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
Y430
N
K
C
A
V
V
K
Y
N
P
N
L
I
A
P
Chicken
Gallus gallus
XP_420307
1494
162045
K318
E
N
K
S
A
I
V
K
Y
N
P
N
L
I
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
V303
N
I
S
K
L
P
A
V
T
S
V
V
V
S
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
A182
A
S
S
P
K
K
R
A
T
P
T
P
P
P
P
Honey Bee
Apis mellifera
XP_395837
1274
139224
M202
I
S
G
F
I
E
E
M
G
F
N
S
F
V
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
0
93.3
N.A.
93.3
93.3
N.A.
46.6
0
N.A.
20
N.A.
13.3
13.3
N.A.
N.A.
P-Site Similarity:
100
N.A.
20
93.3
N.A.
93.3
93.3
N.A.
73.3
26.6
N.A.
40
N.A.
26.6
26.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
0
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
42
9
0
9
9
0
34
0
0
0
9
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% D
% Glu:
9
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
9
0
0
0
0
0
9
0
0
9
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
9
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% H
% Ile:
9
9
0
0
42
9
0
0
0
9
0
0
9
9
0
% I
% Lys:
0
9
9
9
9
9
42
9
0
0
0
0
0
0
9
% K
% Leu:
0
0
0
0
9
9
0
9
0
0
0
34
9
0
9
% L
% Met:
0
0
0
0
0
0
0
9
0
0
0
0
9
0
0
% M
% Asn:
50
17
0
0
0
0
0
0
42
9
17
9
0
0
0
% N
% Pro:
0
0
0
9
0
9
0
0
0
17
9
9
9
9
50
% P
% Gln:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
9
34
0
0
0
0
9
0
9
0
0
0
0
0
0
% R
% Ser:
0
17
50
9
0
0
0
0
0
9
34
17
0
9
0
% S
% Thr:
0
0
0
0
9
0
0
0
17
0
9
0
0
34
9
% T
% Val:
0
0
9
9
9
42
9
9
0
0
9
9
42
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
42
9
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _