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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
13.03
Human Site:
S518
Identified Species:
26.06
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.27
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
S518
R
R
E
E
G
I
Y
S
I
L
V
A
L
M
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
L457
G
S
D
G
N
I
E
L
T
I
T
G
M
T
C
Dog
Lupus familis
XP_549096
1499
164030
S517
R
R
E
E
G
I
Y
S
V
L
V
A
L
M
A
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
K518
L
V
A
L
T
A
G
K
A
E
V
R
Y
N
P
Rat
Rattus norvegicus
P70705
1492
162074
A517
S
V
L
V
A
L
M
A
G
K
A
E
V
R
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
S627
R
R
E
E
G
I
Y
S
V
L
V
A
L
M
A
Chicken
Gallus gallus
XP_420307
1494
162045
M519
H
S
V
L
V
A
L
M
A
G
K
A
E
V
R
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
S503
K
N
E
Y
G
I
H
S
V
L
V
A
L
M
A
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
V378
K
W
R
N
A
F
L
V
S
L
I
F
G
G
P
Honey Bee
Apis mellifera
XP_395837
1274
139224
K398
M
L
F
S
N
R
D
K
E
N
R
D
Y
L
D
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
L118
D
A
G
F
E
A
S
L
I
E
N
E
A
N
E
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
K128
H
V
I
Y
E
P
S
K
T
T
L
E
T
A
R
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
6.6
0
N.A.
93.3
6.6
N.A.
66.6
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
100
N.A.
6.6
20
N.A.
100
13.3
N.A.
86.6
N.A.
20
6.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
17
25
0
9
17
0
9
42
9
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
9
0
9
0
0
0
9
0
0
0
0
9
0
0
9
% D
% Glu:
0
0
34
25
17
0
9
0
9
17
0
25
9
0
9
% E
% Phe:
0
0
9
9
0
9
0
0
0
0
0
9
0
0
0
% F
% Gly:
9
0
9
9
34
0
9
0
9
9
0
9
9
9
0
% G
% His:
17
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
9
0
0
42
0
0
17
9
9
0
0
0
0
% I
% Lys:
17
0
0
0
0
0
0
25
0
9
9
0
0
0
0
% K
% Leu:
9
9
9
17
0
9
17
17
0
42
9
0
34
9
0
% L
% Met:
9
0
0
0
0
0
9
9
0
0
0
0
9
34
0
% M
% Asn:
0
9
0
9
17
0
0
0
0
9
9
0
0
17
0
% N
% Pro:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
17
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
25
25
9
0
0
9
0
0
0
0
9
9
0
9
17
% R
% Ser:
9
17
0
9
0
0
17
34
9
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
0
0
17
9
9
0
9
9
0
% T
% Val:
0
25
9
9
9
0
0
9
25
0
42
0
9
9
0
% V
% Trp:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
17
0
0
25
0
0
0
0
0
17
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _