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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ATP7A
All Species:
7.58
Human Site:
S415
Identified Species:
15.15
UniProt:
Q04656
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q04656
NP_000043.3
1500
163374
S415
I
R
V
S
L
A
N
S
N
G
T
V
E
Y
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103242
1333
143814
L355
V
A
L
H
A
G
S
L
P
T
N
H
L
P
D
Dog
Lupus familis
XP_549096
1499
164030
G415
I
R
V
S
L
A
N
G
N
G
T
V
E
Y
D
Cat
Felis silvestris
Mouse
Mus musculus
Q64430
1491
161891
S415
I
H
V
S
L
A
N
S
T
G
T
I
E
F
D
Rat
Rattus norvegicus
P70705
1492
162074
S415
I
H
V
S
L
T
N
S
T
G
T
I
E
Y
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507266
1609
174606
H524
I
R
I
S
L
A
D
H
N
G
V
V
E
F
D
Chicken
Gallus gallus
XP_420307
1494
162045
H412
I
N
V
S
L
A
N
H
N
G
T
I
E
Y
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001036185
1482
159963
H397
A
Q
V
S
L
A
N
H
Q
G
T
F
E
Y
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_572756
1254
136064
I276
L
G
F
P
T
E
L
I
D
E
P
D
N
G
E
Honey Bee
Apis mellifera
XP_395837
1274
139224
D296
A
E
I
T
F
D
P
D
K
I
R
A
V
D
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SH30
995
108318
F16
T
C
I
R
K
E
R
F
S
E
R
Y
P
L
V
Baker's Yeast
Sacchar. cerevisiae
P38995
1004
109810
A26
T
I
N
T
Q
L
R
A
L
K
G
V
T
K
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
51
92.4
N.A.
89.1
88.7
N.A.
75.1
73.1
N.A.
65.4
N.A.
41.4
44.1
N.A.
N.A.
Protein Similarity:
100
N.A.
67.2
96
N.A.
94.4
94
N.A.
83.5
83.9
N.A.
77.8
N.A.
56.3
58.5
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
93.3
N.A.
73.3
73.3
N.A.
66.6
80
N.A.
66.6
N.A.
0
0
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
86.6
80
N.A.
86.6
86.6
N.A.
73.3
N.A.
20
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
31.3
28.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
45.1
44.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
17
9
0
0
9
50
0
9
0
0
0
9
0
0
0
% A
% Cys:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
9
% C
% Asp:
0
0
0
0
0
9
9
9
9
0
0
9
0
9
67
% D
% Glu:
0
9
0
0
0
17
0
0
0
17
0
0
59
0
9
% E
% Phe:
0
0
9
0
9
0
0
9
0
0
0
9
0
17
0
% F
% Gly:
0
9
0
0
0
9
0
9
0
59
9
0
0
9
0
% G
% His:
0
17
0
9
0
0
0
25
0
0
0
9
0
0
0
% H
% Ile:
50
9
25
0
0
0
0
9
0
9
0
25
0
0
9
% I
% Lys:
0
0
0
0
9
0
0
0
9
9
0
0
0
9
0
% K
% Leu:
9
0
9
0
59
9
9
9
9
0
0
0
9
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
9
0
0
0
50
0
34
0
9
0
9
0
0
% N
% Pro:
0
0
0
9
0
0
9
0
9
0
9
0
9
9
0
% P
% Gln:
0
9
0
0
9
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
0
25
0
9
0
0
17
0
0
0
17
0
0
0
0
% R
% Ser:
0
0
0
59
0
0
9
25
9
0
0
0
0
0
0
% S
% Thr:
17
0
0
17
9
9
0
0
17
9
50
0
9
0
0
% T
% Val:
9
0
50
0
0
0
0
0
0
0
9
34
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
9
0
42
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _