Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP7A All Species: 26.06
Human Site: S1486 Identified Species: 52.12
UniProt: Q04656 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04656 NP_000043.3 1500 163374 S1486 T S E P D K H S L L V G D F R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103242 1333 143814 W1320 A D D G G D K W S L L L N D R
Dog Lupus familis XP_549096 1499 164030 S1485 T S E P D K H S L L V G D Y R
Cat Felis silvestris
Mouse Mus musculus Q64430 1491 161891 S1477 T S E P D K H S L L V G D F R
Rat Rattus norvegicus P70705 1492 162074 S1478 T S E P D K H S L L V G D F R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507266 1609 174606 S1595 L S E P D K H S L L V G D F R
Chicken Gallus gallus XP_420307 1494 162045 S1480 L N E P D K H S L L V G D F G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036185 1482 159963 S1469 L S E P D K H S L L V G D D H
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572756 1254 136064 S1241 G R T K I V R S R F H A N D S
Honey Bee Apis mellifera XP_395837 1274 139224 Y1261 L I T D F S G Y R K N I K D H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SH30 995 108318 L982 N Y K R P K K L D H L E I R E
Baker's Yeast Sacchar. cerevisiae P38995 1004 109810 I991 A I A G E Q D I E S Q A G L M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 51 92.4 N.A. 89.1 88.7 N.A. 75.1 73.1 N.A. 65.4 N.A. 41.4 44.1 N.A. N.A.
Protein Similarity: 100 N.A. 67.2 96 N.A. 94.4 94 N.A. 83.5 83.9 N.A. 77.8 N.A. 56.3 58.5 N.A. N.A.
P-Site Identity: 100 N.A. 13.3 93.3 N.A. 100 100 N.A. 93.3 80 N.A. 80 N.A. 6.6 0 N.A. N.A.
P-Site Similarity: 100 N.A. 33.3 100 N.A. 100 100 N.A. 93.3 86.6 N.A. 80 N.A. 13.3 0 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.3 28.2 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 13.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 0 9 0 0 0 0 0 0 0 0 17 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 9 9 59 9 9 0 9 0 0 0 59 34 0 % D
% Glu: 0 0 59 0 9 0 0 0 9 0 0 9 0 0 9 % E
% Phe: 0 0 0 0 9 0 0 0 0 9 0 0 0 42 0 % F
% Gly: 9 0 0 17 9 0 9 0 0 0 0 59 9 0 9 % G
% His: 0 0 0 0 0 0 59 0 0 9 9 0 0 0 17 % H
% Ile: 0 17 0 0 9 0 0 9 0 0 0 9 9 0 0 % I
% Lys: 0 0 9 9 0 67 17 0 0 9 0 0 9 0 0 % K
% Leu: 34 0 0 0 0 0 0 9 59 67 17 9 0 9 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % M
% Asn: 9 9 0 0 0 0 0 0 0 0 9 0 17 0 0 % N
% Pro: 0 0 0 59 9 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 9 0 0 0 0 9 0 0 0 0 % Q
% Arg: 0 9 0 9 0 0 9 0 17 0 0 0 0 9 50 % R
% Ser: 0 50 0 0 0 9 0 67 9 9 0 0 0 0 9 % S
% Thr: 34 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 9 0 0 0 0 59 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 0 0 9 0 0 0 0 0 9 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _