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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ATP7A All Species: 30.3
Human Site: S1399 Identified Species: 60.61
UniProt: Q04656 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q04656 NP_000043.3 1500 163374 S1399 A M A A S S V S V V L S S L F
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001103242 1333 143814 S1233 A M A A S S V S V V L S S L Q
Dog Lupus familis XP_549096 1499 164030 S1398 A M A A S S V S V V L S S L F
Cat Felis silvestris
Mouse Mus musculus Q64430 1491 161891 S1390 A M A A S S V S V V L S S L F
Rat Rattus norvegicus P70705 1492 162074 S1391 A M A A S S V S V V L S S L F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507266 1609 174606 S1508 A M A A S S V S V V L S S L L
Chicken Gallus gallus XP_420307 1494 162045 S1393 A M A A S S V S V V L S S L L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001036185 1482 159963 S1382 A M A L S S V S V V L S S L L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572756 1254 136064 L1154 R K P T A K T L R T A E Y E A
Honey Bee Apis mellifera XP_395837 1274 139224 L1174 V V G S S L L L K L Y H K P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SH30 995 108318 D895 D I A I E A A D I V L M K S N
Baker's Yeast Sacchar. cerevisiae P38995 1004 109810 W904 R I K L N L F W A L C Y N I F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 51 92.4 N.A. 89.1 88.7 N.A. 75.1 73.1 N.A. 65.4 N.A. 41.4 44.1 N.A. N.A.
Protein Similarity: 100 N.A. 67.2 96 N.A. 94.4 94 N.A. 83.5 83.9 N.A. 77.8 N.A. 56.3 58.5 N.A. N.A.
P-Site Identity: 100 N.A. 93.3 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 0 6.6 N.A. N.A.
P-Site Similarity: 100 N.A. 93.3 100 N.A. 100 100 N.A. 93.3 93.3 N.A. 86.6 N.A. 6.6 33.3 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 31.3 28.2 N.A.
Protein Similarity: N.A. N.A. N.A. 45.1 44.7 N.A.
P-Site Identity: N.A. N.A. N.A. 20 6.6 N.A.
P-Site Similarity: N.A. N.A. N.A. 40 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 75 59 9 9 9 0 9 0 9 0 0 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % C
% Asp: 9 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 9 0 0 0 0 0 0 9 0 9 0 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 42 % F
% Gly: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % H
% Ile: 0 17 0 9 0 0 0 0 9 0 0 0 0 9 0 % I
% Lys: 0 9 9 0 0 9 0 0 9 0 0 0 17 0 0 % K
% Leu: 0 0 0 17 0 17 9 17 0 17 75 0 0 67 25 % L
% Met: 0 67 0 0 0 0 0 0 0 0 0 9 0 0 0 % M
% Asn: 0 0 0 0 9 0 0 0 0 0 0 0 9 0 9 % N
% Pro: 0 0 9 0 0 0 0 0 0 0 0 0 0 9 0 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Q
% Arg: 17 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % R
% Ser: 0 0 0 9 75 67 0 67 0 0 0 67 67 9 0 % S
% Thr: 0 0 0 9 0 0 9 0 0 9 0 0 0 0 9 % T
% Val: 9 9 0 0 0 0 67 0 67 75 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 9 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 9 9 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _