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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL
All Species:
19.39
Human Site:
Y2680
Identified Species:
42.67
UniProt:
Q03164
Number Species:
10
Phosphosite Substitution
Charge Score:
0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03164
NP_005924.2
3969
431764
Y2680
T
S
D
E
D
D
L
Y
Y
Y
N
F
T
R
T
Chimpanzee
Pan troglodytes
XP_508792
3969
431708
Y2680
T
S
D
E
D
D
L
Y
Y
Y
N
F
T
R
T
Rhesus Macaque
Macaca mulatta
XP_001093874
3983
436106
Y2694
T
S
D
E
D
D
L
Y
Y
Y
N
F
T
R
T
Dog
Lupus familis
XP_536554
3923
428640
Y2640
T
S
D
E
D
D
L
Y
Y
Y
N
F
T
R
T
Cat
Felis silvestris
Mouse
Mus musculus
P55200
3966
429631
Y2676
T
S
D
E
D
D
L
Y
Y
Y
N
F
T
R
T
Rat
Rattus norvegicus
NP_001101609
3725
405813
E2462
H
N
L
F
R
E
E
E
Q
C
D
L
P
K
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417896
1716
188201
T478
K
I
S
R
L
E
S
T
P
N
S
R
F
S
A
Frog
Xenopus laevis
Q66J90
1938
216239
H700
P
P
G
V
P
P
H
H
I
L
H
H
P
P
P
Zebra Danio
Brachydanio rerio
NP_001103749
4218
456340
S2926
A
D
D
M
S
T
S
S
S
A
D
S
G
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20659
3726
400080
A2473
G
K
P
L
K
T
V
A
T
K
A
A
Q
Q
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190252
5353
591425
I3895
R
N
V
V
D
E
L
I
D
G
D
L
V
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.8
92.4
N.A.
91.1
85
N.A.
N.A.
33.3
20
46.4
N.A.
20.6
N.A.
N.A.
22.6
Protein Similarity:
100
99.8
96.5
94.3
N.A.
94.2
87.8
N.A.
N.A.
36.5
30.6
59.7
N.A.
36.3
N.A.
N.A.
37.6
P-Site Identity:
100
100
100
100
N.A.
100
0
N.A.
N.A.
0
0
6.6
N.A.
0
N.A.
N.A.
20
P-Site Similarity:
100
100
100
100
N.A.
100
26.6
N.A.
N.A.
13.3
13.3
13.3
N.A.
13.3
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
0
0
10
0
10
10
10
0
0
19
% A
% Cys:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
0
10
55
0
55
46
0
0
10
0
28
0
0
0
10
% D
% Glu:
0
0
0
46
0
28
10
10
0
0
0
0
0
10
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
46
10
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
10
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
10
10
0
0
10
10
0
0
0
% H
% Ile:
0
10
0
0
0
0
0
10
10
0
0
0
0
0
10
% I
% Lys:
10
10
0
0
10
0
0
0
0
10
0
0
0
10
0
% K
% Leu:
0
0
10
10
10
0
55
0
0
10
0
19
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
19
0
0
0
0
0
0
0
10
46
0
0
0
0
% N
% Pro:
10
10
10
0
10
10
0
0
10
0
0
0
19
10
10
% P
% Gln:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% Q
% Arg:
10
0
0
10
10
0
0
0
0
0
0
10
0
55
0
% R
% Ser:
0
46
10
0
10
0
19
10
10
0
10
10
0
10
0
% S
% Thr:
46
0
0
0
0
19
0
10
10
0
0
0
46
0
46
% T
% Val:
0
0
10
19
0
0
10
0
0
0
0
0
10
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
46
46
46
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _