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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL
All Species:
27.27
Human Site:
T3826
Identified Species:
60
UniProt:
Q03164
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03164
NP_005924.2
3969
431764
T3826
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Chimpanzee
Pan troglodytes
XP_508792
3969
431708
T3826
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Rhesus Macaque
Macaca mulatta
XP_001093874
3983
436106
T3840
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Dog
Lupus familis
XP_536554
3923
428640
T3780
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Cat
Felis silvestris
Mouse
Mus musculus
P55200
3966
429631
T3823
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Rat
Rattus norvegicus
NP_001101609
3725
405813
T3582
R
F
R
H
L
K
K
T
S
K
E
A
V
G
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417896
1716
188201
D1595
S
L
F
R
V
N
E
D
L
Y
A
Y
E
C
A
Frog
Xenopus laevis
Q66J90
1938
216239
E1817
D
W
G
L
F
A
M
E
P
I
V
A
D
E
M
Zebra Danio
Brachydanio rerio
NP_001103749
4218
456340
A4075
K
F
R
Q
L
K
K
A
S
R
D
A
V
G
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20659
3726
400080
G3591
E
T
Y
K
D
Y
V
G
V
F
R
S
H
I
H
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190252
5353
591425
T5181
R
F
R
H
L
K
Q
T
A
K
E
A
V
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.8
92.4
N.A.
91.1
85
N.A.
N.A.
33.3
20
46.4
N.A.
20.6
N.A.
N.A.
22.6
Protein Similarity:
100
99.8
96.5
94.3
N.A.
94.2
87.8
N.A.
N.A.
36.5
30.6
59.7
N.A.
36.3
N.A.
N.A.
37.6
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
0
6.6
66.6
N.A.
0
N.A.
N.A.
86.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
13.3
20
86.6
N.A.
6.6
N.A.
N.A.
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
10
0
10
10
0
10
82
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% C
% Asp:
10
0
0
0
10
0
0
10
0
0
10
0
10
0
0
% D
% Glu:
10
0
0
0
0
0
10
10
0
0
64
0
10
10
0
% E
% Phe:
0
73
10
0
10
0
0
0
0
10
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
0
10
0
0
0
0
0
73
0
% G
% His:
0
0
0
64
0
0
0
0
0
0
0
0
10
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
10
0
0
0
10
0
% I
% Lys:
10
0
0
10
0
73
64
0
0
64
0
0
0
0
0
% K
% Leu:
0
10
0
10
73
0
0
0
10
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% P
% Gln:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
64
0
73
10
0
0
0
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
64
0
0
10
0
0
0
% S
% Thr:
0
10
0
0
0
0
0
64
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
10
0
10
0
10
0
73
0
73
% V
% Trp:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
10
0
0
10
0
0
0
10
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _