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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL
All Species:
9.09
Human Site:
T2791
Identified Species:
20
UniProt:
Q03164
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03164
NP_005924.2
3969
431764
T2791
H
S
V
S
R
V
K
T
Q
G
Q
D
S
L
E
Chimpanzee
Pan troglodytes
XP_508792
3969
431708
T2791
H
S
V
S
R
V
K
T
Q
G
Q
D
S
L
E
Rhesus Macaque
Macaca mulatta
XP_001093874
3983
436106
T2805
H
S
V
S
R
V
K
T
Q
G
Q
D
S
L
E
Dog
Lupus familis
XP_536554
3923
428640
A2751
H
S
V
S
R
V
K
A
Q
G
Q
D
S
L
E
Cat
Felis silvestris
Mouse
Mus musculus
P55200
3966
429631
A2787
H
S
V
S
R
V
K
A
Q
G
Q
D
S
L
E
Rat
Rattus norvegicus
NP_001101609
3725
405813
P2570
R
R
V
H
T
S
T
P
S
D
K
N
L
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417896
1716
188201
P585
L
S
A
V
P
S
V
P
Q
Q
Q
S
S
S
S
Frog
Xenopus laevis
Q66J90
1938
216239
K807
P
K
K
E
D
P
H
K
A
T
V
D
G
V
L
Zebra Danio
Brachydanio rerio
NP_001103749
4218
456340
G3044
K
G
S
T
K
R
K
G
R
E
S
R
T
E
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20659
3726
400080
K2580
I
P
T
A
G
E
Y
K
P
Q
P
Q
P
T
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190252
5353
591425
V4088
E
E
K
E
N
E
A
V
K
G
R
R
G
R
P
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.8
92.4
N.A.
91.1
85
N.A.
N.A.
33.3
20
46.4
N.A.
20.6
N.A.
N.A.
22.6
Protein Similarity:
100
99.8
96.5
94.3
N.A.
94.2
87.8
N.A.
N.A.
36.5
30.6
59.7
N.A.
36.3
N.A.
N.A.
37.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
13.3
N.A.
N.A.
26.6
6.6
6.6
N.A.
0
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
93.3
33.3
N.A.
N.A.
26.6
13.3
40
N.A.
6.6
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
10
0
0
10
19
10
0
0
0
0
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
10
0
0
0
0
10
0
55
0
0
10
% D
% Glu:
10
10
0
19
0
19
0
0
0
10
0
0
0
10
46
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
10
0
0
10
0
55
0
0
19
0
0
% G
% His:
46
0
0
10
0
0
10
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
19
0
10
0
55
19
10
0
10
0
0
0
10
% K
% Leu:
10
0
0
0
0
0
0
0
0
0
0
0
10
55
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
10
0
0
0
0
0
0
10
0
0
0
% N
% Pro:
10
10
0
0
10
10
0
19
10
0
10
0
10
0
10
% P
% Gln:
0
0
0
0
0
0
0
0
55
19
55
10
0
0
0
% Q
% Arg:
10
10
0
0
46
10
0
0
10
0
10
19
0
10
0
% R
% Ser:
0
55
10
46
0
19
0
0
10
0
10
10
55
10
10
% S
% Thr:
0
0
10
10
10
0
10
28
0
10
0
0
10
10
0
% T
% Val:
0
0
55
10
0
46
10
10
0
0
10
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _