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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MLL
All Species:
13.03
Human Site:
S2554
Identified Species:
28.67
UniProt:
Q03164
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q03164
NP_005924.2
3969
431764
S2554
P
L
Q
I
E
S
T
S
P
T
E
P
I
S
A
Chimpanzee
Pan troglodytes
XP_508792
3969
431708
S2554
P
L
Q
I
E
S
T
S
P
T
E
P
I
S
A
Rhesus Macaque
Macaca mulatta
XP_001093874
3983
436106
S2568
P
L
Q
I
E
S
T
S
P
P
E
P
I
S
A
Dog
Lupus familis
XP_536554
3923
428640
S2514
P
L
Q
M
E
S
A
S
P
T
E
P
V
S
A
Cat
Felis silvestris
Mouse
Mus musculus
P55200
3966
429631
A2552
H
I
E
S
V
C
P
A
E
P
V
S
A
S
R
Rat
Rattus norvegicus
NP_001101609
3725
405813
Q2344
D
P
Q
S
N
N
Y
Q
N
L
P
E
Q
D
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_417896
1716
188201
Q360
N
S
Q
L
E
K
P
Q
R
I
R
K
E
K
D
Frog
Xenopus laevis
Q66J90
1938
216239
Q582
R
S
A
S
P
I
D
Q
I
N
Q
P
V
R
K
Zebra Danio
Brachydanio rerio
NP_001103749
4218
456340
Q2790
T
P
S
N
Q
G
P
Q
R
R
S
S
R
A
M
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P20659
3726
400080
Q2355
F
G
L
Q
G
L
Q
Q
L
Q
L
Q
P
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001190252
5353
591425
C3596
S
V
G
S
L
K
S
C
L
T
S
T
V
S
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
95.8
92.4
N.A.
91.1
85
N.A.
N.A.
33.3
20
46.4
N.A.
20.6
N.A.
N.A.
22.6
Protein Similarity:
100
99.8
96.5
94.3
N.A.
94.2
87.8
N.A.
N.A.
36.5
30.6
59.7
N.A.
36.3
N.A.
N.A.
37.6
P-Site Identity:
100
100
93.3
80
N.A.
6.6
6.6
N.A.
N.A.
13.3
6.6
0
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
100
93.3
93.3
N.A.
26.6
13.3
N.A.
N.A.
20
20
13.3
N.A.
6.6
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
10
0
0
0
10
10
0
0
0
0
10
10
37
% A
% Cys:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% C
% Asp:
10
0
0
0
0
0
10
0
0
0
0
0
0
10
10
% D
% Glu:
0
0
10
0
46
0
0
0
10
0
37
10
10
0
10
% E
% Phe:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
10
0
10
10
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
10
0
28
0
10
0
0
10
10
0
0
28
0
0
% I
% Lys:
0
0
0
0
0
19
0
0
0
0
0
10
0
10
10
% K
% Leu:
0
37
10
10
10
10
0
0
19
10
10
0
0
0
0
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
10
0
0
10
10
10
0
0
10
10
0
0
0
0
0
% N
% Pro:
37
19
0
0
10
0
28
0
37
19
10
46
10
0
0
% P
% Gln:
0
0
55
10
10
0
10
46
0
10
10
10
10
10
0
% Q
% Arg:
10
0
0
0
0
0
0
0
19
10
10
0
10
10
19
% R
% Ser:
10
19
10
37
0
37
10
37
0
0
19
19
0
55
10
% S
% Thr:
10
0
0
0
0
0
28
0
0
37
0
10
0
0
0
% T
% Val:
0
10
0
0
10
0
0
0
0
0
10
0
28
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _