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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CREM All Species: 16.97
Human Site: T350 Identified Species: 46.67
UniProt: Q03060 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q03060 NP_874393.1 361 38940 T350 K L I E E L E T L K D I C S P
Chimpanzee Pan troglodytes XP_001148291 349 37380 T338 K L I E E L E T L K D I C S P
Rhesus Macaque Macaca mulatta XP_001090829 349 37431 A339 T L I E E L K A L K D L Y C H
Dog Lupus familis XP_860529 351 37709 A341 T L I E E L K A L K D L Y C H
Cat Felis silvestris
Mouse Mus musculus P27699 357 38498 T347 K L I E E L E T L K D I C S P
Rat Rattus norvegicus Q03061 357 38479 T347 K L I E E L E T L K D I C S P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508739 318 34413 A308 T L I E E L K A L K D L Y C H
Chicken Gallus gallus NP_989781 327 35075 A317 T L I E E L K A L K D L Y C H
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VWW0 359 37920 S348 A L I E E L K S L K E L Y C Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 95.8 88.9 59.2 N.A. 90 90 N.A. 69.8 59 N.A. N.A. N.A. 21.6 N.A. N.A. N.A.
Protein Similarity: 100 96.1 91.6 73.6 N.A. 93.9 93.9 N.A. 78.1 71.4 N.A. N.A. N.A. 36.2 N.A. N.A. N.A.
P-Site Identity: 100 100 53.3 53.3 N.A. 100 100 N.A. 53.3 53.3 N.A. N.A. N.A. 46.6 N.A. N.A. N.A.
P-Site Similarity: 100 100 66.6 66.6 N.A. 100 100 N.A. 66.6 66.6 N.A. N.A. N.A. 73.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 0 0 0 0 0 45 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 45 56 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 89 0 0 0 0 % D
% Glu: 0 0 0 100 100 0 45 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % H
% Ile: 0 0 100 0 0 0 0 0 0 0 0 45 0 0 0 % I
% Lys: 45 0 0 0 0 0 56 0 0 100 0 0 0 0 0 % K
% Leu: 0 100 0 0 0 100 0 0 100 0 0 56 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % P
% Gln: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 12 0 0 0 0 0 45 0 % S
% Thr: 45 0 0 0 0 0 0 45 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 56 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _