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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MAP3K10
All Species:
11.21
Human Site:
S498
Identified Species:
24.67
UniProt:
Q02779
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.1
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02779
NP_002437.2
954
103694
S498
T
L
D
K
R
K
G
S
D
G
A
S
P
P
A
Chimpanzee
Pan troglodytes
XP_001146659
1107
121909
N547
D
K
R
K
S
L
I
N
S
R
S
S
P
P
A
Rhesus Macaque
Macaca mulatta
XP_001091512
949
103262
S495
T
L
D
K
R
K
G
S
D
G
A
S
P
P
A
Dog
Lupus familis
XP_547887
1216
135201
N656
D
K
R
K
S
L
I
N
S
R
S
S
P
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q66L42
940
103168
S498
T
L
D
K
R
K
G
S
D
G
A
S
P
P
A
Rat
Rattus norvegicus
Q66HA1
850
93091
R473
D
R
E
R
P
H
V
R
R
R
R
G
T
F
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Q7T2V3
1005
111856
Q516
M
L
D
K
C
K
G
Q
G
T
S
S
Y
S
P
Zebra Danio
Brachydanio rerio
XP_689424
1050
114747
S538
L
L
K
L
G
R
D
S
N
C
I
S
L
P
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q95UN8
1161
128942
Q592
N
L
D
K
K
Q
Q
Q
Q
N
Q
Q
Q
V
A
Honey Bee
Apis mellifera
XP_395037
1102
123539
G571
K
L
N
K
K
E
P
G
S
N
I
S
A
P
S
Nematode Worm
Caenorhab. elegans
O01700
928
103465
G504
A
P
R
A
Q
L
R
G
Y
P
N
E
G
Y
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
52.3
94.3
46.5
N.A.
92.1
46.7
N.A.
N.A.
N.A.
60.9
59.2
N.A.
31.8
34.2
20.3
N.A.
Protein Similarity:
100
63.7
95.8
57.2
N.A.
94.3
58
N.A.
N.A.
N.A.
71
68.7
N.A.
45.3
48.6
35.9
N.A.
P-Site Identity:
100
33.3
100
33.3
N.A.
100
0
N.A.
N.A.
N.A.
40
26.6
N.A.
26.6
26.6
0
N.A.
P-Site Similarity:
100
46.6
100
46.6
N.A.
100
13.3
N.A.
N.A.
N.A.
46.6
46.6
N.A.
40
53.3
6.6
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
0
0
0
0
0
0
28
0
10
0
55
% A
% Cys:
0
0
0
0
10
0
0
0
0
10
0
0
0
0
0
% C
% Asp:
28
0
46
0
0
0
10
0
28
0
0
0
0
0
10
% D
% Glu:
0
0
10
0
0
10
0
0
0
0
0
10
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
0
10
0
37
19
10
28
0
10
10
0
0
% G
% His:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
19
0
0
0
19
0
0
0
0
% I
% Lys:
10
19
10
73
19
37
0
0
0
0
0
0
0
0
10
% K
% Leu:
10
64
0
10
0
28
0
0
0
0
0
0
10
0
0
% L
% Met:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
10
0
0
0
0
19
10
19
10
0
0
0
0
% N
% Pro:
0
10
0
0
10
0
10
0
0
10
0
0
46
64
10
% P
% Gln:
0
0
0
0
10
10
10
19
10
0
10
10
10
0
0
% Q
% Arg:
0
10
28
10
28
10
10
10
10
28
10
0
0
0
0
% R
% Ser:
0
0
0
0
19
0
0
37
28
0
28
73
0
10
19
% S
% Thr:
28
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% T
% Val:
0
0
0
0
0
0
10
0
0
0
0
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
10
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _