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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MAP3K10 All Species: 8.79
Human Site: S446 Identified Species: 19.33
UniProt: Q02779 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02779 NP_002437.2 954 103694 S446 H L L M C Q L S Q E K P R V R
Chimpanzee Pan troglodytes XP_001146659 1107 121909 C495 N I I I H Q L C Q E K P R V K
Rhesus Macaque Macaca mulatta XP_001091512 949 103262 S443 H L L M C Q L S Q E K P R V R
Dog Lupus familis XP_547887 1216 135201 C604 N I I I H Q L C Q E K P R V K
Cat Felis silvestris
Mouse Mus musculus Q66L42 940 103168 S446 H L L M S Q L S Q E K P R V R
Rat Rattus norvegicus Q66HA1 850 93091 E422 E K E L L S R E E E L T R A A
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus
Frog Xenopus laevis Q7T2V3 1005 111856 N459 D I V E R E L N I I M Y Q M Y
Zebra Danio Brachydanio rerio XP_689424 1050 114747 Q482 A A E E Q R E Q E E H L R R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q95UN8 1161 128942 P487 L V M L Q P V P S K R K H K K
Honey Bee Apis mellifera XP_395037 1102 123539 H515 A Q V Q Q R Q H E E N L R Q R
Nematode Worm Caenorhab. elegans O01700 928 103465 N453 E M K L K R T N K M Y D K L Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 52.3 94.3 46.5 N.A. 92.1 46.7 N.A. N.A. N.A. 60.9 59.2 N.A. 31.8 34.2 20.3 N.A.
Protein Similarity: 100 63.7 95.8 57.2 N.A. 94.3 58 N.A. N.A. N.A. 71 68.7 N.A. 45.3 48.6 35.9 N.A.
P-Site Identity: 100 53.3 100 53.3 N.A. 93.3 13.3 N.A. N.A. N.A. 6.6 20 N.A. 0 20 0 N.A.
P-Site Similarity: 100 86.6 100 86.6 N.A. 93.3 26.6 N.A. N.A. N.A. 46.6 33.3 N.A. 46.6 40 53.3 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 19 10 0 0 0 0 0 0 0 0 0 0 0 10 10 % A
% Cys: 0 0 0 0 19 0 0 19 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % D
% Glu: 19 0 19 19 0 10 10 10 28 73 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 28 0 0 0 19 0 0 10 0 0 10 0 10 0 0 % H
% Ile: 0 28 19 19 0 0 0 0 10 10 0 0 0 0 0 % I
% Lys: 0 10 10 0 10 0 0 0 10 10 46 10 10 10 28 % K
% Leu: 10 28 28 28 10 0 55 0 0 0 10 19 0 10 0 % L
% Met: 0 10 10 28 0 0 0 0 0 10 10 0 0 10 0 % M
% Asn: 19 0 0 0 0 0 0 19 0 0 10 0 0 0 0 % N
% Pro: 0 0 0 0 0 10 0 10 0 0 0 46 0 0 0 % P
% Gln: 0 10 0 10 28 46 10 10 46 0 0 0 10 10 10 % Q
% Arg: 0 0 0 0 10 28 10 0 0 0 10 0 73 10 46 % R
% Ser: 0 0 0 0 10 10 0 28 10 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 0 0 10 0 0 0 0 10 0 0 0 % T
% Val: 0 10 19 0 0 0 10 0 0 0 0 0 0 46 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 10 10 0 0 10 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _