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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF23 All Species: 18.79
Human Site: S482 Identified Species: 31.79
UniProt: Q02241 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02241 NP_004847.2 960 110059 S482 Q S F P P L P S C E I L D I N
Chimpanzee Pan troglodytes XP_001174899 959 109984 S482 Q S F P P L P S C E I L D I N
Rhesus Macaque Macaca mulatta XP_001086180 956 109643 S482 Q S F P P L P S C E I L D I N
Dog Lupus familis XP_535528 929 106546 S459 Q S F P P L P S C E L L D I N
Cat Felis silvestris
Mouse Mus musculus NP_077207 953 108757 P483 Q S F P P L P P C K L L D I N
Rat Rattus norvegicus NP_001101625 952 108772 P482 Q S F P P L P P C K L L D V N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508348 973 110874 S494 Q S L P P L T S C E L L D V N
Chicken Gallus gallus Q5ZLK6 797 86563 L377 Y A T I C E Q L K T E V A D L
Frog Xenopus laevis NP_001088544 783 89786 N363 N R L R E A G N I N Q S L M T
Zebra Danio Brachydanio rerio A8WFU8 634 70574 K214 N R T T A S T K L N Q R S S R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_477025 887 100649 L466 P M K Q D L G L T P G R R K A
Honey Bee Apis mellifera XP_624886 843 96284 E423 P R T D D Y D E T I Q V M K F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_999659 870 99519 A444 T T H V M R F A E I T Q E V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P53086 805 91072 S385 C L N D G S R S C H I P Y R D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 98.7 91.7 N.A. 88.9 88.8 N.A. 83.6 21.9 61.7 26 N.A. 38.6 40.2 N.A. 45.3
Protein Similarity: 100 99.6 99.1 94.3 N.A. 94.7 95 N.A. 90.6 38.6 70 40 N.A. 58 58.3 N.A. 61.9
P-Site Identity: 100 100 100 93.3 N.A. 80 73.3 N.A. 73.3 0 0 0 N.A. 6.6 0 N.A. 0
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 86.6 13.3 13.3 0 N.A. 6.6 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 22.6 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 40.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 20 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 8 0 0 8 8 0 8 0 0 0 0 8 0 8 % A
% Cys: 8 0 0 0 8 0 0 0 58 0 0 0 0 0 0 % C
% Asp: 0 0 0 15 15 0 8 0 0 0 0 0 50 8 8 % D
% Glu: 0 0 0 0 8 8 0 8 8 36 8 0 8 0 0 % E
% Phe: 0 0 43 0 0 0 8 0 0 0 0 0 0 0 8 % F
% Gly: 0 0 0 0 8 0 15 0 0 0 8 0 0 0 0 % G
% His: 0 0 8 0 0 0 0 0 0 8 0 0 0 0 0 % H
% Ile: 0 0 0 8 0 0 0 0 8 15 29 0 0 36 0 % I
% Lys: 0 0 8 0 0 0 0 8 8 15 0 0 0 15 0 % K
% Leu: 0 8 15 0 0 58 0 15 8 0 29 50 8 0 8 % L
% Met: 0 8 0 0 8 0 0 0 0 0 0 0 8 8 0 % M
% Asn: 15 0 8 0 0 0 0 8 0 15 0 0 0 0 50 % N
% Pro: 15 0 0 50 50 0 43 15 0 8 0 8 0 0 0 % P
% Gln: 50 0 0 8 0 0 8 0 0 0 22 8 0 0 8 % Q
% Arg: 0 22 0 8 0 8 8 0 0 0 0 15 8 8 8 % R
% Ser: 0 50 0 0 0 15 0 43 0 0 0 8 8 8 0 % S
% Thr: 8 8 22 8 0 0 15 0 15 8 8 0 0 0 8 % T
% Val: 0 0 0 8 0 0 0 0 0 0 0 15 0 22 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 8 0 0 0 0 0 0 8 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _