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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KIF23
All Species:
29.39
Human Site:
S249
Identified Species:
49.74
UniProt:
Q02241
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02241
NP_004847.2
960
110059
S249
I
K
P
K
P
P
Q
S
K
L
L
R
E
D
K
Chimpanzee
Pan troglodytes
XP_001174899
959
109984
S249
I
K
P
K
P
P
Q
S
K
L
L
R
E
D
K
Rhesus Macaque
Macaca mulatta
XP_001086180
956
109643
S249
I
K
P
K
P
P
Q
S
K
L
L
R
E
D
K
Dog
Lupus familis
XP_535528
929
106546
S225
I
K
P
K
P
P
Q
S
K
L
L
R
E
D
K
Cat
Felis silvestris
Mouse
Mus musculus
NP_077207
953
108757
S249
I
K
P
K
L
P
Q
S
K
T
L
R
E
D
K
Rat
Rattus norvegicus
NP_001101625
952
108772
S249
I
K
P
K
L
P
Q
S
K
M
L
R
E
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508348
973
110874
S249
I
K
P
K
P
P
Q
S
K
I
L
R
E
D
K
Chicken
Gallus gallus
Q5ZLK6
797
86563
L167
Y
N
E
Q
I
H
D
L
L
E
P
K
G
P
L
Frog
Xenopus laevis
NP_001088544
783
89786
Y153
G
D
F
Q
A
K
R
Y
V
F
K
L
D
E
K
Zebra Danio
Brachydanio rerio
A8WFU8
634
70574
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_477025
887
100649
S253
V
Y
D
L
L
E
D
S
G
I
Q
K
T
L
Q
Honey Bee
Apis mellifera
XP_624886
843
96284
Q213
I
E
E
T
E
T
I
Q
V
D
Q
D
N
V
Y
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999659
870
99519
F234
E
D
N
N
Y
A
I
F
V
S
Y
V
E
I
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P53086
805
91072
P175
V
Y
K
E
T
T
S
P
L
L
D
S
V
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
98.7
91.7
N.A.
88.9
88.8
N.A.
83.6
21.9
61.7
26
N.A.
38.6
40.2
N.A.
45.3
Protein Similarity:
100
99.6
99.1
94.3
N.A.
94.7
95
N.A.
90.6
38.6
70
40
N.A.
58
58.3
N.A.
61.9
P-Site Identity:
100
100
100
100
N.A.
86.6
86.6
N.A.
93.3
0
6.6
0
N.A.
6.6
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
86.6
93.3
N.A.
100
13.3
33.3
0
N.A.
33.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
22.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
15
8
0
0
0
15
0
0
8
8
8
8
50
8
% D
% Glu:
8
8
15
8
8
8
0
0
0
8
0
0
58
8
0
% E
% Phe:
0
0
8
0
0
0
0
8
0
8
0
0
0
0
0
% F
% Gly:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
58
0
0
0
8
0
15
0
0
15
0
0
0
8
0
% I
% Lys:
0
50
8
50
0
8
0
0
50
0
8
15
0
0
58
% K
% Leu:
0
0
0
8
22
0
0
8
15
36
50
8
0
15
8
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
0
0
0
0
0
0
8
0
0
% N
% Pro:
0
0
50
0
36
50
0
8
0
0
8
0
0
8
0
% P
% Gln:
0
0
0
15
0
0
50
8
0
0
15
0
0
0
8
% Q
% Arg:
0
0
0
0
0
0
8
0
0
0
0
50
0
0
0
% R
% Ser:
0
0
0
0
0
0
8
58
0
8
0
8
0
0
0
% S
% Thr:
0
0
0
8
8
15
0
0
0
8
0
0
8
0
0
% T
% Val:
15
0
0
0
0
0
0
0
22
0
0
8
8
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
15
0
0
8
0
0
8
0
0
8
0
0
0
15
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _