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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
OGDH
All Species:
40.61
Human Site:
Y508
Identified Species:
74.44
UniProt:
Q02218
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02218
NP_001003941.1
1023
115935
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Chimpanzee
Pan troglodytes
XP_001146956
1023
115904
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Rhesus Macaque
Macaca mulatta
XP_001089063
1023
115873
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Dog
Lupus familis
XP_532722
881
99572
R430
I
G
F
T
T
D
P
R
M
A
R
S
S
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q60597
1023
116430
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Rat
Rattus norvegicus
Q5XI78
1023
116277
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509039
937
105661
V484
A
V
I
Y
V
C
G
V
A
A
E
W
R
N
T
Chicken
Gallus gallus
NP_001026553
1016
115163
Y503
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Frog
Xenopus laevis
Q6P6Z8
1021
115614
Y507
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Zebra Danio
Brachydanio rerio
NP_957073
1022
115620
Y508
V
V
V
D
L
V
C
Y
R
R
N
G
H
N
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_391838
1029
116125
Y523
V
V
I
D
I
V
S
Y
R
R
N
G
H
N
E
Nematode Worm
Caenorhab. elegans
O61199
1029
115643
Y512
V
I
V
D
L
V
C
Y
R
R
H
G
H
N
E
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P20967
1014
114398
W503
A
I
I
D
V
V
G
W
R
K
H
G
H
N
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.9
80.4
N.A.
95.8
96.2
N.A.
73
91.4
90.1
86.5
N.A.
N.A.
65.1
56.1
N.A.
Protein Similarity:
100
99.9
99.9
82.4
N.A.
97.5
97.8
N.A.
80.6
95
93.7
92.8
N.A.
N.A.
77.6
73.2
N.A.
P-Site Identity:
100
100
100
0
N.A.
100
100
N.A.
13.3
100
100
100
N.A.
N.A.
80
86.6
N.A.
P-Site Similarity:
100
100
100
6.6
N.A.
100
100
N.A.
26.6
100
100
100
N.A.
N.A.
93.3
100
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
46.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
63.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
0
0
0
0
0
0
0
8
16
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
8
70
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
85
0
8
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
85
% E
% Phe:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
0
0
0
0
16
0
0
0
0
85
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
16
0
85
0
0
% H
% Ile:
8
16
24
0
8
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% K
% Leu:
0
0
0
0
70
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
70
0
0
93
0
% N
% Pro:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
8
85
77
8
0
8
0
0
% R
% Ser:
0
0
0
0
0
0
8
0
0
0
0
8
8
0
0
% S
% Thr:
0
0
0
8
8
0
0
0
0
0
0
0
0
0
8
% T
% Val:
77
77
70
0
16
85
0
8
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
77
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _