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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OGDH All Species: 43.64
Human Site: S274 Identified Species: 80
UniProt: Q02218 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02218 NP_001003941.1 1023 115935 S274 F L Q R K W S S E K R F G L E
Chimpanzee Pan troglodytes XP_001146956 1023 115904 S274 F L Q R K W S S E K R F G L E
Rhesus Macaque Macaca mulatta XP_001089063 1023 115873 S274 F L Q R K W S S E K R F G L E
Dog Lupus familis XP_532722 881 99572 E216 Q W I R Q K F E T P G I M Q F
Cat Felis silvestris
Mouse Mus musculus Q60597 1023 116430 S274 F L Q R K W S S E K R F G L E
Rat Rattus norvegicus Q5XI78 1023 116277 S274 F L Q R K W S S E K R F G L E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509039 937 105661 S269 F L A R K W S S E K R F G L E
Chicken Gallus gallus NP_001026553 1016 115163 S269 F L H R K W S S E K R F G L E
Frog Xenopus laevis Q6P6Z8 1021 115614 S273 F L H R K W S S E K R F G L E
Zebra Danio Brachydanio rerio NP_957073 1022 115620 S274 F L Q R K W S S E K R F G L E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_391838 1029 116125 S290 F L A R K W S S E K R F G L E
Nematode Worm Caenorhab. elegans O61199 1029 115643 S279 F L A K K W P S E K R F G L E
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P20967 1014 114398 N268 F L S T K F P N D K R F G L E
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.9 99.9 80.4 N.A. 95.8 96.2 N.A. 73 91.4 90.1 86.5 N.A. N.A. 65.1 56.1 N.A.
Protein Similarity: 100 99.9 99.9 82.4 N.A. 97.5 97.8 N.A. 80.6 95 93.7 92.8 N.A. N.A. 77.6 73.2 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 100 N.A. 93.3 93.3 93.3 100 N.A. N.A. 93.3 80 N.A.
P-Site Similarity: 100 100 100 13.3 N.A. 100 100 N.A. 93.3 93.3 93.3 100 N.A. N.A. 93.3 86.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 46.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 63.6 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 60 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 80 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 24 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 8 85 0 0 0 0 0 93 % E
% Phe: 93 0 0 0 0 8 8 0 0 0 0 93 0 0 8 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 8 0 93 0 0 % G
% His: 0 0 16 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 8 0 0 0 0 0 0 0 0 8 0 0 0 % I
% Lys: 0 0 0 8 93 8 0 0 0 93 0 0 0 0 0 % K
% Leu: 0 93 0 0 0 0 0 0 0 0 0 0 0 93 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % M
% Asn: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 16 0 0 8 0 0 0 0 0 % P
% Gln: 8 0 47 0 8 0 0 0 0 0 0 0 0 8 0 % Q
% Arg: 0 0 0 85 0 0 0 0 0 0 93 0 0 0 0 % R
% Ser: 0 0 8 0 0 0 77 85 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 8 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 8 0 0 0 85 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _