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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MEF2B
All Species:
17.58
Human Site:
Y229
Identified Species:
32.22
UniProt:
Q02080
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q02080
NP_005910.1
365
38639
Y229
L
N
T
S
R
S
L
Y
S
G
L
Q
N
P
C
Chimpanzee
Pan troglodytes
XP_512521
368
39108
Y229
L
S
T
S
R
S
L
Y
S
G
L
Q
N
P
C
Rhesus Macaque
Macaca mulatta
XP_001115695
368
39170
Y229
L
N
T
S
R
S
L
Y
S
G
L
Q
S
P
C
Dog
Lupus familis
XP_852158
417
45078
L294
R
P
D
L
P
G
S
L
A
G
A
R
G
G
L
Cat
Felis silvestris
Mouse
Mus musculus
O55087
349
37416
Y223
L
G
T
S
R
S
L
Y
S
G
L
Q
S
P
G
Rat
Rattus norvegicus
O89038
507
54350
L300
V
S
Q
S
T
H
S
L
T
T
P
V
V
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509613
423
45590
Y235
L
S
S
T
R
T
L
Y
S
S
L
Q
N
S
S
Chicken
Gallus gallus
Q9W6U8
499
53650
G224
G
A
G
T
S
P
V
G
N
G
V
W
N
S
R
Frog
Xenopus laevis
Q03414
516
56328
D370
M
P
T
A
Y
N
T
D
Y
P
L
T
S
A
D
Zebra Danio
Brachydanio rerio
XP_686335
420
46059
S240
L
A
N
A
V
R
E
S
T
K
R
A
L
Y
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P40791
539
57097
G268
M
S
A
P
D
D
V
G
Y
A
D
Q
R
Q
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38847
268
30310
K149
Q
L
E
E
S
R
L
K
E
Q
R
A
E
L
E
Baker's Yeast
Sacchar. cerevisiae
P38128
452
49396
H230
L
L
L
S
E
S
N
H
S
N
Y
H
N
F
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
73.6
72
61.8
N.A.
58.9
36.4
N.A.
54.1
33.8
32.9
38
N.A.
32.2
N.A.
N.A.
N.A.
Protein Similarity:
100
77.7
76.6
64.9
N.A.
66.8
46.3
N.A.
61.2
44.6
43.2
48
N.A.
41
N.A.
N.A.
N.A.
P-Site Identity:
100
93.3
93.3
6.6
N.A.
80
6.6
N.A.
53.3
13.3
13.3
6.6
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
86.6
26.6
N.A.
80
40
40
20
N.A.
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
23.5
23.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
40
36.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
33.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
8
16
0
0
0
0
8
8
8
16
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
24
% C
% Asp:
0
0
8
0
8
8
0
8
0
0
8
0
0
0
8
% D
% Glu:
0
0
8
8
8
0
8
0
8
0
0
0
8
0
8
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% F
% Gly:
8
8
8
0
0
8
0
16
0
47
0
0
8
8
8
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
8
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
8
0
8
0
0
0
0
0
% K
% Leu:
54
16
8
8
0
0
47
16
0
0
47
0
8
8
8
% L
% Met:
16
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
16
8
0
0
8
8
0
8
8
0
0
39
0
0
% N
% Pro:
0
16
0
8
8
8
0
0
0
8
8
0
0
31
0
% P
% Gln:
8
0
8
0
0
0
0
0
0
8
0
47
0
8
8
% Q
% Arg:
8
0
0
0
39
16
0
0
0
0
16
8
8
0
8
% R
% Ser:
0
31
8
47
16
39
16
8
47
8
0
0
24
24
16
% S
% Thr:
0
0
39
16
8
8
8
0
16
8
0
8
0
0
0
% T
% Val:
8
0
0
0
8
0
16
0
0
0
8
8
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
8
0
0
39
16
0
8
0
0
8
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _