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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MEF2B All Species: 4.85
Human Site: S286 Identified Species: 8.89
UniProt: Q02080 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q02080 NP_005910.1 365 38639 S286 S A S S L S A S L R P P G A P
Chimpanzee Pan troglodytes XP_512521 368 39108 G283 A P W Q P S R G D G P P A V P
Rhesus Macaque Macaca mulatta XP_001115695 368 39170 G283 A P W Q P S R G D G P P A V P
Dog Lupus familis XP_852158 417 45078 A337 L P A G P P A A P P Q P S G A
Cat Felis silvestris
Mouse Mus musculus O55087 349 37416 A270 P W P P T R D A V D P A R P V
Rat Rattus norvegicus O89038 507 54350 I422 T V T T H P H I S I K S E P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509613 423 45590 S306 S L H S Q L G S V A A R I P P
Chicken Gallus gallus Q9W6U8 499 53650 S383 L S S L V S G S Q L S Q G S N
Frog Xenopus laevis Q03414 516 56328 F411 G Q A A L S S F V A T G Q L S
Zebra Danio Brachydanio rerio XP_686335 420 46059 P307 A H Q S M I S P G M A S G G S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P40791 539 57097 S380 G S T G S G G S S S S T S S N
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38847 268 30310 P189 I K C F A I D P K N A L I N H
Baker's Yeast Sacchar. cerevisiae P38128 452 49396 N367 T D V Q A T P N Q M L A S N M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 73.6 72 61.8 N.A. 58.9 36.4 N.A. 54.1 33.8 32.9 38 N.A. 32.2 N.A. N.A. N.A.
Protein Similarity: 100 77.7 76.6 64.9 N.A. 66.8 46.3 N.A. 61.2 44.6 43.2 48 N.A. 41 N.A. N.A. N.A.
P-Site Identity: 100 26.6 26.6 13.3 N.A. 6.6 0 N.A. 26.6 26.6 13.3 13.3 N.A. 6.6 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 33.3 26.6 N.A. 20 20 N.A. 33.3 46.6 40 33.3 N.A. 26.6 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 23.5 23.2 N.A.
Protein Similarity: N.A. N.A. N.A. 40 36.9 N.A.
P-Site Identity: N.A. N.A. N.A. 0 0 N.A.
P-Site Similarity: N.A. N.A. N.A. 0 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 16 8 16 0 16 16 0 16 24 16 16 8 8 % A
% Cys: 0 0 8 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 8 0 0 0 0 16 0 16 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 8 0 0 % E
% Phe: 0 0 0 8 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 16 0 0 16 0 8 24 16 8 16 0 8 24 16 0 % G
% His: 0 8 8 0 8 0 8 0 0 0 0 0 0 0 8 % H
% Ile: 8 0 0 0 0 16 0 8 0 8 0 0 16 0 0 % I
% Lys: 0 8 0 0 0 0 0 0 8 0 8 0 0 0 0 % K
% Leu: 16 8 0 8 16 8 0 0 8 8 8 8 0 8 0 % L
% Met: 0 0 0 0 8 0 0 0 0 16 0 0 0 0 8 % M
% Asn: 0 0 0 0 0 0 0 8 0 8 0 0 0 16 16 % N
% Pro: 8 24 8 8 24 16 8 16 8 8 31 31 0 24 31 % P
% Gln: 0 8 8 24 8 0 0 0 16 0 8 8 8 0 0 % Q
% Arg: 0 0 0 0 0 8 16 0 0 8 0 8 8 0 0 % R
% Ser: 16 16 16 24 8 39 16 31 16 8 16 16 24 16 16 % S
% Thr: 16 0 16 8 8 8 0 0 0 0 8 8 0 0 0 % T
% Val: 0 8 8 0 8 0 0 0 24 0 0 0 0 16 16 % V
% Trp: 0 8 16 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _