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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCB3 All Species: 19.39
Human Site: S1227 Identified Species: 42.67
UniProt: Q01970 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q01970 NP_000923.1 1234 138799 S1227 L S G A D S E S Q E E N T Q L
Chimpanzee Pan troglodytes XP_001170216 1271 144286 K1251 D P G K V N H K T P S S E E L
Rhesus Macaque Macaca mulatta XP_001115104 1234 138637 S1227 L S G A D S E S Q E E N T Q L
Dog Lupus familis XP_853283 1230 138739 S1223 L S G A D S E S Q E E N T K L
Cat Felis silvestris
Mouse Mus musculus P51432 1234 139473 S1227 L S S A D S E S Q E E N T Q L
Rat Rattus norvegicus Q99JE6 1234 139431 S1227 Q S G A D S E S Q E E N T Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513474 1217 138978 N1208 E E G L E E D N P E K V F D T
Chicken Gallus gallus Q2VRL0 637 72514
Frog Xenopus laevis Q32NH8 758 87399
Zebra Danio Brachydanio rerio NP_001116245 1244 141781 S1222 S N I A N V S S L L L D S S T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25455 1318 146373 N1308 I S P A K S H N S I A A A A E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 53.7 96.3 93.1 N.A. 91.9 92 N.A. 53.2 23.1 22.7 58.4 N.A. 40.3 N.A. N.A. N.A.
Protein Similarity: 100 70 97.1 96.1 N.A. 94.8 94.7 N.A. 71.5 32.6 35.4 74.3 N.A. 56.8 N.A. N.A. N.A.
P-Site Identity: 100 13.3 100 93.3 N.A. 93.3 93.3 N.A. 13.3 0 0 13.3 N.A. 20 N.A. N.A. N.A.
P-Site Similarity: 100 33.3 100 100 N.A. 93.3 93.3 N.A. 40 0 0 40 N.A. 33.3 N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 64 0 0 0 0 0 0 10 10 10 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 46 0 10 0 0 0 0 10 0 10 0 % D
% Glu: 10 10 0 0 10 10 46 0 0 55 46 0 10 10 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 55 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 19 0 0 0 0 0 0 0 0 % H
% Ile: 10 0 10 0 0 0 0 0 0 10 0 0 0 0 0 % I
% Lys: 0 0 0 10 10 0 0 10 0 0 10 0 0 10 0 % K
% Leu: 37 0 0 10 0 0 0 0 10 10 10 0 0 0 55 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 10 0 0 10 10 0 19 0 0 0 46 0 0 0 % N
% Pro: 0 10 10 0 0 0 0 0 10 10 0 0 0 0 0 % P
% Gln: 10 0 0 0 0 0 0 0 46 0 0 0 0 37 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 55 10 0 0 55 10 55 10 0 10 10 10 10 0 % S
% Thr: 0 0 0 0 0 0 0 0 10 0 0 0 46 0 19 % T
% Val: 0 0 0 0 10 10 0 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _