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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC10
All Species:
10.61
Human Site:
S669
Identified Species:
21.21
UniProt:
Q01780
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01780
NP_002676.1
885
100831
S669
N
E
P
S
A
E
D
S
K
K
G
P
L
T
V
Chimpanzee
Pan troglodytes
XP_514382
885
100746
S669
N
E
P
S
A
E
D
S
K
K
G
P
L
T
V
Rhesus Macaque
Macaca mulatta
XP_001103014
884
100980
N669
N
E
P
S
A
E
D
N
K
K
G
P
L
T
I
Dog
Lupus familis
XP_535408
1012
115406
S796
N
E
P
S
A
E
E
S
G
K
S
P
L
T
V
Cat
Felis silvestris
Mouse
Mus musculus
P56960
887
100953
G669
S
E
P
N
T
E
E
G
G
K
T
P
L
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012748
910
103885
G694
S
E
C
D
K
D
E
G
N
E
K
V
L
T
T
Frog
Xenopus laevis
NP_001084822
883
101879
I664
N
G
F
E
D
E
E
I
P
S
K
S
W
S
V
Zebra Danio
Brachydanio rerio
NP_957383
899
102353
P665
L
F
A
E
D
V
S
P
A
S
A
H
L
T
V
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097795
900
102900
E652
S
K
P
T
Q
E
E
E
Q
R
W
A
H
L
R
Honey Bee
Apis mellifera
XP_396975
722
84430
T514
M
L
L
N
I
A
E
T
L
P
R
E
M
Q
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198503
819
91757
D606
E
G
Q
R
S
T
N
D
L
S
G
P
S
V
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12149
733
84020
S525
E
A
T
P
I
P
S
S
E
T
K
A
D
G
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
77.9
N.A.
87
N.A.
N.A.
N.A.
70.8
65.1
59.8
N.A.
30.7
34.5
N.A.
38.7
Protein Similarity:
100
99.8
98.6
82.2
N.A.
92.2
N.A.
N.A.
N.A.
82.6
79.8
75.8
N.A.
51.1
53.4
N.A.
56.2
P-Site Identity:
100
100
86.6
80
N.A.
53.3
N.A.
N.A.
N.A.
20
20
20
N.A.
13.3
0
N.A.
13.3
P-Site Similarity:
100
100
100
86.6
N.A.
73.3
N.A.
N.A.
N.A.
46.6
33.3
20
N.A.
53.3
26.6
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
9
0
34
9
0
0
9
0
9
17
0
0
0
% A
% Cys:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
9
17
9
25
9
0
0
0
0
9
0
0
% D
% Glu:
17
50
0
17
0
59
50
9
9
9
0
9
0
0
9
% E
% Phe:
0
9
9
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
0
0
0
0
0
17
17
0
34
0
0
9
9
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
9
9
0
0
% H
% Ile:
0
0
0
0
17
0
0
9
0
0
0
0
0
0
17
% I
% Lys:
0
9
0
0
9
0
0
0
25
42
25
0
0
0
0
% K
% Leu:
9
9
9
0
0
0
0
0
17
0
0
0
59
9
0
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
42
0
0
17
0
0
9
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
50
9
0
9
0
9
9
9
0
50
0
0
0
% P
% Gln:
0
0
9
0
9
0
0
0
9
0
0
0
0
9
0
% Q
% Arg:
0
0
0
9
0
0
0
0
0
9
9
0
0
0
9
% R
% Ser:
25
0
0
34
9
0
17
34
0
25
9
9
9
9
0
% S
% Thr:
0
0
9
9
9
9
0
9
0
9
9
0
0
59
9
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
9
0
9
50
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
9
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _