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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EXOSC10
All Species:
12.73
Human Site:
S628
Identified Species:
25.45
UniProt:
Q01780
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01780
NP_002676.1
885
100831
S628
P
I
I
P
T
S
G
S
V
P
V
Q
K
Q
A
Chimpanzee
Pan troglodytes
XP_514382
885
100746
S628
P
I
I
P
T
S
G
S
V
P
V
Q
K
Q
A
Rhesus Macaque
Macaca mulatta
XP_001103014
884
100980
S628
P
I
I
P
T
N
G
S
V
P
V
Q
K
Q
A
Dog
Lupus familis
XP_535408
1012
115406
V755
M
M
P
S
N
G
P
V
P
A
Q
K
Q
A
S
Cat
Felis silvestris
Mouse
Mus musculus
P56960
887
100953
T628
Q
N
T
S
T
D
G
T
L
P
L
Q
K
Q
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001012748
910
103885
E653
S
T
S
A
P
V
L
E
R
D
S
L
F
S
D
Frog
Xenopus laevis
NP_001084822
883
101879
L623
H
L
Y
S
G
T
G
L
Q
L
L
E
G
S
L
Zebra Danio
Brachydanio rerio
NP_957383
899
102353
T624
L
D
L
S
S
F
E
T
P
T
K
P
G
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_001097795
900
102900
R611
D
L
P
T
L
L
K
R
N
S
T
T
G
K
L
Honey Bee
Apis mellifera
XP_396975
722
84430
F473
Y
R
K
S
Q
K
M
F
N
N
K
Q
L
Y
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198503
819
91757
K565
N
K
E
G
K
V
K
K
G
E
V
F
A
S
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q12149
733
84020
V484
P
T
D
V
I
G
V
V
S
L
T
N
G
V
T
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
97.8
77.9
N.A.
87
N.A.
N.A.
N.A.
70.8
65.1
59.8
N.A.
30.7
34.5
N.A.
38.7
Protein Similarity:
100
99.8
98.6
82.2
N.A.
92.2
N.A.
N.A.
N.A.
82.6
79.8
75.8
N.A.
51.1
53.4
N.A.
56.2
P-Site Identity:
100
100
93.3
0
N.A.
40
N.A.
N.A.
N.A.
0
6.6
0
N.A.
0
13.3
N.A.
6.6
P-Site Similarity:
100
100
100
26.6
N.A.
60
N.A.
N.A.
N.A.
0
33.3
20
N.A.
13.3
13.3
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.1
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
46.3
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
9
0
0
0
0
0
9
0
0
9
9
34
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
9
9
0
0
9
0
0
0
9
0
0
0
0
9
% D
% Glu:
0
0
9
0
0
0
9
9
0
9
0
9
0
0
0
% E
% Phe:
0
0
0
0
0
9
0
9
0
0
0
9
9
0
0
% F
% Gly:
0
0
0
9
9
17
42
0
9
0
0
0
34
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
25
25
0
9
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
9
9
17
9
0
0
17
9
34
9
9
% K
% Leu:
9
17
9
0
9
9
9
9
9
17
17
9
9
0
25
% L
% Met:
9
9
0
0
0
0
9
0
0
0
0
0
0
9
0
% M
% Asn:
9
9
0
0
9
9
0
0
17
9
0
9
0
0
0
% N
% Pro:
34
0
17
25
9
0
9
0
17
34
0
9
0
0
9
% P
% Gln:
9
0
0
0
9
0
0
0
9
0
9
42
9
34
0
% Q
% Arg:
0
9
0
0
0
0
0
9
9
0
0
0
0
0
0
% R
% Ser:
9
0
9
42
9
17
0
25
9
9
9
0
0
25
9
% S
% Thr:
0
17
9
9
34
9
0
17
0
9
17
9
0
0
9
% T
% Val:
0
0
0
9
0
17
9
17
25
0
34
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
9
0
0
0
0
0
0
0
0
0
0
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _