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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MC2R
All Species:
14.85
Human Site:
Y91
Identified Species:
36.3
UniProt:
Q01718
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01718
NP_000520.1
297
33927
Y91
I
I
L
R
N
M
G
Y
L
K
P
R
G
S
F
Chimpanzee
Pan troglodytes
Q9TT23
325
36628
H103
I
Y
L
L
N
N
K
H
L
V
I
A
D
A
F
Rhesus Macaque
Macaca mulatta
Q864J4
317
34745
A105
T
L
L
L
E
A
G
A
L
V
A
R
A
A
V
Dog
Lupus familis
XP_541098
296
33644
Y91
I
V
F
R
N
M
G
Y
L
K
P
R
G
N
F
Cat
Felis silvestris
Mouse
Mus musculus
Q64326
296
33963
Y91
I
M
F
R
N
M
G
Y
L
K
P
R
G
S
F
Rat
Rattus norvegicus
P70596
332
36868
T110
V
I
T
L
L
N
S
T
D
T
D
A
Q
S
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507879
326
36917
Y103
I
I
L
K
N
K
G
Y
L
G
P
L
G
D
F
Chicken
Gallus gallus
P55167
314
35279
V103
M
L
L
M
E
H
G
V
L
V
I
R
A
S
I
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_775385
326
36403
N108
M
A
L
I
T
G
G
N
L
T
N
R
E
S
I
Tiger Blowfish
Takifugu rubipres
NP_001027732
322
35956
T106
I
A
L
I
N
S
G
T
L
T
I
P
A
T
L
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
43.3
38.1
90.2
N.A.
88.5
45.7
N.A.
66.2
41.7
N.A.
46.3
46.8
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
64
54.5
95.2
N.A.
96.3
62.9
N.A.
79.4
61.7
N.A.
64.1
64.9
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
33.3
26.6
80
N.A.
86.6
20
N.A.
66.6
33.3
N.A.
33.3
33.3
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
46.6
40
93.3
N.A.
93.3
26.6
N.A.
73.3
46.6
N.A.
40
40
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
10
0
10
0
0
10
20
30
20
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
10
0
10
0
10
10
0
% D
% Glu:
0
0
0
0
20
0
0
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
60
% F
% Gly:
0
0
0
0
0
10
80
0
0
10
0
0
40
0
0
% G
% His:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
60
30
0
20
0
0
0
0
0
0
30
0
0
0
20
% I
% Lys:
0
0
0
10
0
10
10
0
0
30
0
0
0
0
0
% K
% Leu:
0
20
70
30
10
0
0
0
90
0
0
10
0
0
10
% L
% Met:
20
10
0
10
0
30
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
60
20
0
10
0
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
40
10
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% Q
% Arg:
0
0
0
30
0
0
0
0
0
0
0
60
0
0
0
% R
% Ser:
0
0
0
0
0
10
10
0
0
0
0
0
0
50
0
% S
% Thr:
10
0
10
0
10
0
0
20
0
30
0
0
0
10
0
% T
% Val:
10
10
0
0
0
0
0
10
0
30
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
10
0
0
0
0
0
40
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _