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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMPD2
All Species:
5.76
Human Site:
Y349
Identified Species:
11.52
UniProt:
Q01433
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01433
NP_004028.3
879
100688
Y349
C
S
E
V
E
L
P
Y
P
D
L
Q
E
F
V
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093312
879
100639
Y349
C
S
E
V
E
L
P
Y
P
D
L
Q
E
F
V
Dog
Lupus familis
XP_852599
799
92011
V324
E
L
A
A
Q
K
K
V
P
H
R
D
F
Y
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT5
798
92005
V324
E
L
A
A
Q
K
K
V
P
H
R
D
F
Y
N
Rat
Rattus norvegicus
Q02356
824
94769
Y327
F
C
Y
R
R
L
Q
Y
L
S
S
K
F
Q
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700028
819
94934
K326
R
L
Q
Y
L
S
S
K
F
Q
M
H
I
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727741
774
89333
L300
M
H
V
L
L
N
E
L
R
E
L
A
A
Q
K
Honey Bee
Apis mellifera
XP_623550
773
88695
L298
K
Y
Q
L
H
V
L
L
N
E
L
R
E
L
A
Nematode Worm
Caenorhab. elegans
NP_001040752
803
92339
F326
L
S
Y
L
E
N
K
F
Q
L
H
V
L
L
N
Sea Urchin
Strong. purpuratus
XP_792615
845
97202
L327
Y
P
D
R
S
T
F
L
I
D
S
N
K
M
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80452
839
95111
F329
V
A
D
A
T
A
F
F
T
D
L
H
H
V
L
Baker's Yeast
Sacchar. cerevisiae
P15274
810
93283
E327
Y
R
R
L
Q
Y
L
E
A
R
W
N
L
Y
Y
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
89.5
N.A.
88.6
91.4
N.A.
N.A.
N.A.
N.A.
72.5
N.A.
52.5
54
46.8
48.3
Protein Similarity:
100
N.A.
99.8
90.2
N.A.
89.3
92
N.A.
N.A.
N.A.
N.A.
82
N.A.
67.4
65.9
60.9
63.2
P-Site Identity:
100
N.A.
100
6.6
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
0
N.A.
6.6
13.3
13.3
6.6
P-Site Similarity:
100
N.A.
100
20
N.A.
20
26.6
N.A.
N.A.
N.A.
N.A.
20
N.A.
20
46.6
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
41.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
40
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
17
25
0
9
0
0
9
0
0
9
9
0
9
% A
% Cys:
17
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
0
0
0
0
0
0
34
0
17
0
0
0
% D
% Glu:
17
0
17
0
25
0
9
9
0
17
0
0
25
0
0
% E
% Phe:
9
0
0
0
0
0
17
17
9
0
0
0
25
17
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
9
0
0
9
0
0
0
0
17
9
17
9
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
9
0
0
0
9
0
0
% I
% Lys:
9
0
0
0
0
17
25
9
0
0
0
9
9
0
9
% K
% Leu:
9
25
0
34
17
25
17
25
9
9
42
0
17
25
25
% L
% Met:
9
0
0
0
0
0
0
0
0
0
9
0
0
9
9
% M
% Asn:
0
0
0
0
0
17
0
0
9
0
0
17
0
0
25
% N
% Pro:
0
9
0
0
0
0
17
0
34
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
25
0
9
0
9
9
0
17
0
17
0
% Q
% Arg:
9
9
9
17
9
0
0
0
9
9
17
9
0
0
0
% R
% Ser:
0
25
0
0
9
9
9
0
0
9
17
0
0
0
0
% S
% Thr:
0
0
0
0
9
9
0
0
9
0
0
0
0
0
0
% T
% Val:
9
0
9
17
0
9
0
17
0
0
0
9
0
9
17
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% W
% Tyr:
17
9
17
9
0
9
0
25
0
0
0
0
0
25
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _