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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AMPD2
All Species:
24.24
Human Site:
T455
Identified Species:
48.48
UniProt:
Q01433
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01433
NP_004028.3
879
100688
T455
V
E
Q
G
R
E
Q
T
L
R
E
V
F
E
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001093312
879
100639
T455
V
E
Q
G
R
E
Q
T
L
R
E
V
F
E
S
Dog
Lupus familis
XP_852599
799
92011
D393
T
A
Y
D
L
S
V
D
T
L
D
M
H
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9DBT5
798
92005
D393
T
A
Y
D
L
S
V
D
T
L
D
V
H
A
D
Rat
Rattus norvegicus
Q02356
824
94769
T401
V
E
Q
G
R
E
Q
T
L
R
E
V
F
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_700028
819
94934
T396
V
E
Q
G
R
G
Q
T
L
T
E
V
F
E
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_727741
774
89333
N369
A
Q
V
F
Q
S
M
N
L
T
T
Y
D
L
T
Honey Bee
Apis mellifera
XP_623550
773
88695
F367
T
M
T
L
R
E
V
F
Q
S
M
N
L
T
T
Nematode Worm
Caenorhab. elegans
NP_001040752
803
92339
T395
N
N
N
G
T
K
V
T
M
K
E
V
F
K
K
Sea Urchin
Strong. purpuratus
XP_792615
845
97202
T428
K
K
L
G
R
A
L
T
L
K
E
V
F
D
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O80452
839
95111
T428
F
R
D
G
T
Y
L
T
L
R
E
V
F
E
S
Baker's Yeast
Sacchar. cerevisiae
P15274
810
93283
T399
F
R
D
G
K
L
L
T
L
D
E
V
F
R
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
99.6
89.5
N.A.
88.6
91.4
N.A.
N.A.
N.A.
N.A.
72.5
N.A.
52.5
54
46.8
48.3
Protein Similarity:
100
N.A.
99.8
90.2
N.A.
89.3
92
N.A.
N.A.
N.A.
N.A.
82
N.A.
67.4
65.9
60.9
63.2
P-Site Identity:
100
N.A.
100
0
N.A.
6.6
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
6.6
13.3
33.3
53.3
P-Site Similarity:
100
N.A.
100
13.3
N.A.
13.3
100
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
26.6
20
60
73.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
42.5
41.7
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
57.4
57.6
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
60
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
60
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
17
0
0
0
9
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
17
17
0
0
0
17
0
9
17
0
9
9
17
% D
% Glu:
0
34
0
0
0
34
0
0
0
0
67
0
0
42
0
% E
% Phe:
17
0
0
9
0
0
0
9
0
0
0
0
67
0
0
% F
% Gly:
0
0
0
67
0
9
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
17
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
9
9
0
0
9
9
0
0
0
17
0
0
0
9
9
% K
% Leu:
0
0
9
9
17
9
25
0
67
17
0
0
9
9
0
% L
% Met:
0
9
0
0
0
0
9
0
9
0
9
9
0
0
0
% M
% Asn:
9
9
9
0
0
0
0
9
0
0
0
9
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
9
34
0
9
0
34
0
9
0
0
0
0
0
0
% Q
% Arg:
0
17
0
0
50
0
0
0
0
34
0
0
0
9
0
% R
% Ser:
0
0
0
0
0
25
0
0
0
9
0
0
0
0
59
% S
% Thr:
25
0
9
0
17
0
0
67
17
17
9
0
0
9
17
% T
% Val:
34
0
9
0
0
0
34
0
0
0
0
75
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
17
0
0
9
0
0
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _