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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SCN7A
All Species:
1.82
Human Site:
T448
Identified Species:
4.44
UniProt:
Q01118
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01118
NP_002967.2
1682
193473
T448
R
S
P
I
S
T
D
T
S
L
D
V
L
E
D
Chimpanzee
Pan troglodytes
XP_515875
1687
193906
S448
A
S
R
A
A
G
K
S
N
P
E
S
M
T
S
Rhesus Macaque
Macaca mulatta
XP_001116451
1837
208223
A502
G
E
A
D
G
D
P
A
H
G
K
D
C
N
G
Dog
Lupus familis
XP_545504
1677
192583
L442
P
T
S
I
I
T
S
L
N
M
L
D
D
A
A
Cat
Felis silvestris
Mouse
Mus musculus
Q9ER60
1841
208779
P495
G
E
E
A
D
G
D
P
T
H
S
K
D
C
N
Rat
Rattus norvegicus
P15390
1840
208848
P495
G
E
E
A
D
G
D
P
T
H
N
K
D
C
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513667
1993
226281
M461
S
A
G
G
G
R
G
M
V
L
S
E
S
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q20JQ7
1784
201644
N476
S
S
K
K
K
G
D
N
D
Q
M
Q
S
D
Y
Tiger Blowfish
Takifugu rubipres
Q2XVR6
1719
196461
L478
G
F
E
D
D
H
R
L
C
P
P
C
W
Y
A
Fruit Fly
Dros. melanogaster
P35500
2131
239344
E483
A
D
A
A
A
A
E
E
A
A
L
H
P
E
M
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.2
46.8
80.1
N.A.
46.9
47
N.A.
49.2
N.A.
N.A.
45.5
45.9
32.9
N.A.
N.A.
N.A.
Protein Similarity:
100
98.4
63
88.8
N.A.
63
63.3
N.A.
63.6
N.A.
N.A.
64.5
64.4
50.1
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
0
13.3
N.A.
6.6
6.6
N.A.
6.6
N.A.
N.A.
13.3
0
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
40
0
33.3
N.A.
20
26.6
N.A.
13.3
N.A.
N.A.
20
0
26.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
20
40
20
10
0
10
10
10
0
0
0
10
20
% A
% Cys:
0
0
0
0
0
0
0
0
10
0
0
10
10
20
0
% C
% Asp:
0
10
0
20
30
10
40
0
10
0
10
20
30
10
10
% D
% Glu:
0
30
30
0
0
0
10
10
0
0
10
10
0
20
0
% E
% Phe:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
40
0
10
10
20
40
10
0
0
10
0
0
0
0
10
% G
% His:
0
0
0
0
0
10
0
0
10
20
0
10
0
0
0
% H
% Ile:
0
0
0
20
10
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
10
10
0
10
0
0
0
10
20
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
20
0
20
20
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
10
0
10
10
0
10
0
10
% M
% Asn:
0
0
0
0
0
0
0
10
20
0
10
0
0
10
20
% N
% Pro:
10
0
10
0
0
0
10
20
0
20
10
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
10
0
0
0
% Q
% Arg:
10
0
10
0
0
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
20
30
10
0
10
0
10
10
10
0
20
10
20
10
20
% S
% Thr:
0
10
0
0
0
20
0
10
20
0
0
0
0
10
0
% T
% Val:
0
0
0
0
0
0
0
0
10
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _