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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TIAL1
All Species:
27.88
Human Site:
S252
Identified Species:
51.11
UniProt:
Q01085
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q01085
NP_001029097.1
375
41591
S252
V
R
F
S
T
H
E
S
A
A
H
A
I
V
S
Chimpanzee
Pan troglodytes
XP_001154825
563
61985
S440
V
R
F
S
T
H
E
S
A
A
H
A
I
V
S
Rhesus Macaque
Macaca mulatta
XP_001098686
375
41755
S250
V
R
F
N
S
H
E
S
A
A
H
A
I
V
S
Dog
Lupus familis
XP_865325
381
42336
V258
E
S
A
A
H
A
I
V
S
V
N
G
T
T
I
Cat
Felis silvestris
Mouse
Mus musculus
P70318
392
43370
S269
V
R
F
S
T
H
E
S
A
A
H
A
I
V
S
Rat
Rattus norvegicus
Q9EPH8
636
70682
Q384
H
L
T
N
Q
Y
M
Q
R
M
A
S
V
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514793
386
43037
S266
V
R
F
S
T
H
E
S
A
A
H
A
I
V
S
Chicken
Gallus gallus
NP_989687
388
42938
S268
V
R
F
S
T
H
E
S
A
A
H
A
I
V
S
Frog
Xenopus laevis
P20965
633
70449
E345
V
C
F
S
S
P
E
E
A
T
K
A
V
T
E
Zebra Danio
Brachydanio rerio
NP_957426
370
41210
S251
I
R
F
S
S
H
E
S
A
A
H
A
I
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q09442
388
40990
T271
P
P
P
P
P
S
V
T
P
M
P
P
P
M
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P42731
629
68654
P417
V
R
P
V
A
M
Q
P
S
V
G
P
R
M
P
Baker's Yeast
Sacchar. cerevisiae
P32588
453
50771
H331
V
N
P
Q
A
V
D
H
I
I
R
S
A
P
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
59.3
80
98.4
N.A.
94.9
22
N.A.
85.2
94
20.7
85.8
N.A.
N.A.
N.A.
22.1
N.A.
Protein Similarity:
100
62.1
87.4
98.4
N.A.
95.1
32.3
N.A.
89.6
94.3
32.2
92.2
N.A.
N.A.
N.A.
37.3
N.A.
P-Site Identity:
100
100
86.6
0
N.A.
100
0
N.A.
100
100
40
86.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
33.3
N.A.
100
100
53.3
100
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.3
24
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
34.5
39.9
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
33.3
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
8
8
16
8
0
0
62
54
8
62
8
0
8
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% D
% Glu:
8
0
0
0
0
0
62
8
0
0
0
0
0
0
8
% E
% Phe:
0
0
62
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% G
% His:
8
0
0
0
8
54
0
8
0
0
54
0
0
0
0
% H
% Ile:
8
0
0
0
0
0
8
0
8
8
0
0
54
0
8
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
8
8
0
0
16
0
0
0
16
0
% M
% Asn:
0
8
0
16
0
0
0
0
0
0
8
0
0
0
0
% N
% Pro:
8
8
24
8
8
8
0
8
8
0
8
16
8
8
24
% P
% Gln:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
0
% Q
% Arg:
0
62
0
0
0
0
0
0
8
0
8
0
8
8
0
% R
% Ser:
0
8
0
54
24
8
0
54
16
0
0
16
0
0
54
% S
% Thr:
0
0
8
0
39
0
0
8
0
8
0
0
8
16
0
% T
% Val:
70
0
0
8
0
8
8
8
0
16
0
0
16
54
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _