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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCB2
All Species:
25.15
Human Site:
Y1127
Identified Species:
50.3
UniProt:
Q00722
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00722
NP_004564.2
1185
134024
Y1127
Q
K
E
A
L
A
E
Y
E
A
R
M
K
G
L
Chimpanzee
Pan troglodytes
XP_001141721
1185
134063
Y1127
Q
K
E
A
L
A
E
Y
E
A
R
M
K
G
L
Rhesus Macaque
Macaca mulatta
XP_001095135
1181
134067
Y1123
Q
K
E
A
L
A
E
Y
E
A
R
M
K
G
L
Dog
Lupus familis
XP_544615
1188
134303
Y1130
Q
Q
E
A
L
A
E
Y
E
A
R
M
K
G
L
Cat
Felis silvestris
Mouse
Mus musculus
A3KGF7
1181
134528
Y1123
Q
E
K
A
L
A
E
Y
E
A
K
M
K
G
L
Rat
Rattus norvegicus
O89040
1183
134864
Y1125
Q
E
K
A
L
A
E
Y
E
A
K
M
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513474
1217
138978
Y1150
Q
V
E
L
D
Q
E
Y
Q
D
K
F
K
R
L
Chicken
Gallus gallus
Q2VRL0
637
72514
D596
E
I
S
L
V
A
N
D
F
L
G
Q
Y
T
L
Frog
Xenopus laevis
Q32NH8
758
87399
F717
V
G
Q
Y
T
L
P
F
K
S
I
K
S
G
Y
Zebra Danio
Brachydanio rerio
NP_001116245
1244
141781
F1158
Q
A
R
L
T
R
D
F
E
A
E
L
K
R
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
H1238
V
R
N
A
L
A
E
H
R
S
K
A
R
Q
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q944C2
578
66234
D537
Y
N
M
P
E
K
D
D
F
S
G
Q
T
C
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
96.1
91.5
N.A.
85.9
85.9
N.A.
44.7
21.5
23.9
42.5
N.A.
35.8
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
97.5
94.9
N.A.
90.7
90.8
N.A.
65.3
33.9
35.4
61.1
N.A.
54
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
93.3
N.A.
80
80
N.A.
40
13.3
6.6
33.3
N.A.
26.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
53.3
26.6
33.3
53.3
N.A.
66.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
31.5
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
59
0
67
0
0
0
59
0
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
0
0
0
0
9
0
17
17
0
9
0
0
0
0
0
% D
% Glu:
9
17
42
0
9
0
67
0
59
0
9
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
17
17
0
0
9
0
0
0
% F
% Gly:
0
9
0
0
0
0
0
0
0
0
17
0
0
59
0
% G
% His:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% H
% Ile:
0
9
0
0
0
0
0
0
0
0
9
0
0
0
9
% I
% Lys:
0
25
17
0
0
9
0
0
9
0
34
9
67
0
0
% K
% Leu:
0
0
0
25
59
9
0
0
0
9
0
9
0
0
84
% L
% Met:
0
0
9
0
0
0
0
0
0
0
0
50
0
0
0
% M
% Asn:
0
9
9
0
0
0
9
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
0
0
9
0
0
0
0
0
0
0
0
% P
% Gln:
67
9
9
0
0
9
0
0
9
0
0
17
0
9
0
% Q
% Arg:
0
9
9
0
0
9
0
0
9
0
34
0
9
17
0
% R
% Ser:
0
0
9
0
0
0
0
0
0
25
0
0
9
0
0
% S
% Thr:
0
0
0
0
17
0
0
0
0
0
0
0
9
9
0
% T
% Val:
17
9
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
9
0
0
9
0
0
0
59
0
0
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _